Robert Tycko

{{short description|American biophysicist}}

Robert Tycko is an American biophysicist whose research primarily involves solid state NMR, including the development of new methods and applications{{cite journal|title= Citations of 'Theory for cross effect dynamic nuclear polarization under magic-angle spinning in solid state nuclear magnetic resonance: The importance of level crossings;, K.R. Thurber and R. Tycko, J. Chem. Phys. 137, 084508|journal= The Journal of Chemical Physics|volume= 137|issue= 8|pages= 084508|doi= 10.1063/1.4747449|pmid= 22938251|pmc= 3443114|year = 2012|last1 = Thurber|first1 = Kent R.|last2= Tycko|first2= Robert}} to various areas of physics, chemistry, and biology.{{cite web|url=http://spin.niddk.nih.gov/tycko/oldwork.html |title= Robert Tycko NIH Profile: Past Work}} He is a member of the Laboratory of Chemical Physics in the National Institute of Diabetes and Digestive and Kidney Diseases at the National Institutes of Health in Bethesda, Maryland, USA.{{cite web|url=http://spin.niddk.nih.gov/tycko/ |title= Robert Tycko NIH Lab Website}} He was formerly a member of the Physical Chemistry Research and Materials Chemistry Research departments of AT&T Bell Labs in Murray Hill, New Jersey. His work has contributed to our understanding of geometric phases in spectroscopy,{{cite journal|title= Citations of 'Adiabatic rotational splitting and Berry's phase in nuclear quadrupole resonance", R. Tycko, Phys. Rev. Lett. 58, 2281'|journal= Physical Review Letters|volume= 58|issue= 22|pages= 2281–2284|doi= 10.1103/PhysRevLett.58.2281|pmid= 10034704|year = 1987|last1 = Tycko|first1 = Robert}} physical properties of fullerenes,{{cite journal|title= Citations of 'Molecular dynamics and the phase transition in solid C60'|journal= Physical Review Letters|volume= 67|issue= 14|pages= 1886–1889|doi= 10.1103/PhysRevLett.67.1886|pmid= 10044276|year = 1991|last1 = Tycko|first1 = R.|last2= Dabbagh|first2= G.|last3= Fleming|first3= R. M.|last4= Haddon|first4= R. C.|last5= Makhija|first5= A. V.|last6= Zahurak|first6= S. M.}} skyrmions in 2D electron systems,{{cite web|url=https://scholar.google.com/scholar?es_sm=93&bav=on.2,or.r_qf.&bvm=bv.75774317,d.cWc,pv.xjs.s.en_US.8Rnrv8-hPjQ.O&biw=1745&bih=829&um=1&ie=UTF-8&lr=&cites=15443457591768467907 |title= Citations of 'Optically pumped NMR evidence for finite-size skyrmions in GaAs quantum wells near Landau level filling ν = 1', S.E. Barrett et al., Phys. Rev. Lett. 74, 5112 }} protein folding,{{cite journal|title= Citations of 'Detection of a transient intermediate in a rapid protein folding process by solid state nuclear magnetic resonance', K.-N. Hu, W.-M. Yau, and R. Tycko, J. Am. Chem. Soc. 132, 24 |journal= Journal of the American Chemical Society |volume= 132 |issue= 1 |pages= 24–25 |doi= 10.1021/ja908471n |pmid= 20000466 |pmc= 2805027 |year = 2010|last1 = Hu|first1 = Kan-Nian|last2= Yau |first2= Wai-Ming |last3= Tycko |first3= Robert }} and amyloid fibrils{{cite journal|title= Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils |journal= Science |volume= 307 |issue= 5707 |pages= 262–265 |doi= 10.1126/science.1105850 |pmid= 15653506 |year= 2005 |last1= Petkova |first1= A. T. |last2= Leapman |first2= R. D. |last3= Guo |first3= Z. |last4= Yau |first4= W. M. |last5= Mattson |first5= M. P. |last6= Tycko |first6= R. |bibcode= 2005Sci...307..262P |s2cid= 24176417 }} associated with Alzheimer’s disease and prions.