Rolf Huisgen
{{Use dmy dates|date=February 2021}}
{{Short description|German chemist (1920–2020)}}
{{Infobox scientist
| name = Rolf Huisgen
| image = Rolf Huisgen.JPG
| image_size =
| alt =
| caption = Rolf Huisgen in 2004
| birth_date = 13 June 1920
| birth_place = Gerolstein, Rhineland-Palatinate, Germany
| death_date = {{death date and age|2020|03|26|1920|06|13|df=yes}}
| death_place = Munich, Bavaria, Germany
| field = Chemist
| work_institution = University of Munich
| alma_mater = University of Munich
| doctoral_advisor = Heinrich Otto Wieland
| known_for = 1,3-dipolar cycloaddition reaction
| prizes = 1960 Centenary Prize
1961 Liebig Medal
1979 Otto Hahn Prize for Chemistry and Physics
}}
Rolf Huisgen ({{IPA|de|'huːzgɛn|lang}}; 13 June 1920 – 26 March 2020) was a German chemist. His importance in synthetic organic chemistry extends to the enormous influence he had in post-war chemistry departments in Germany and Austria, due to a large number of his habilitants becoming professors. His major achievement was the development of the 1,3-dipolar cycloaddition reaction, also called the Huisgen cycloaddition.
Life
Huisgen was born in Gerolstein in Rhineland-Palatinate and studied in Munich under the supervision of Heinrich Otto Wieland. He completed his Ph.D. in 1943 with a thesis about a strychnine alkaloid. He completed his habilitation in 1947, and was appointed professor at the University of Tübingen in 1949. He returned to the University of Munich in 1952, succeeding Wieland, and he remained dedicated to research long after attaining emeritus status there in 1988.
One of his major achievements was the development of the 1,3-dipolar cycloaddition reaction, also known as the Huisgen cycloaddition or Huisgen reaction.{{cite journal|title=Kinetics and Mechanism of 1,3-Dipolar Cycloadditions|first=Rolf|last=Huisgen|journal=Angewandte Chemie International Edition|volume=2|issue=11|date=November 1963|pages=633–645|url=http://www3.interscience.wiley.com/cgi-bin/abstract/106572717/ABSTRACT|archive-url=https://archive.today/20121211070409/http://www3.interscience.wiley.com/cgi-bin/abstract/106572717/ABSTRACT|url-status=dead|archive-date=11 December 2012|doi=10.1002/anie.196306331}}{{cite journal|title=1,3-Dipolar Cycloadditions. Past and Future|first=Rolf|last=Huisgen|journal=Angewandte Chemie International Edition|volume=2|issue=10|date=October 1963|pages=565–598|url=http://www3.interscience.wiley.com/cgi-bin/abstract/106572678/ABSTRACT|archive-url=https://archive.today/20121216135529/http://www3.interscience.wiley.com/cgi-bin/abstract/106572678/ABSTRACT|url-status=dead|archive-date=16 December 2012|doi=10.1002/anie.196305651}} The Huisgen reaction is of paramount importance to the synthesis of heterocyclic compounds, such as vitamins, alkaloids and antibiotics.
Huisgen was a member of the American Academy of Arts and Sciences from 1960.[https://www.amacad.org/person/rolf-huisgen Dr. Rolf Huisgen] American Academy of Arts and Sciences He was also a member of the German National Academy of Sciences Leopoldina and an Honorary Fellow of the Royal Society of Chemistry. He was an Honorary Member of the Gesellschaft Deutscher Chemiker and the Chemical Society of Japan. He was awarded the Liebig Medal in 1961, the Lavoisier Medal from the Société Chimique de France in 1965, and the Adolfo Quilico Medal from the Società Chimica Italiana in 1987, among others. He was elected to the National Academy of Sciences in 1989.[http://www.nasonline.org/member-directory/members/4576.html Rolf Huisgen] National Academy of Sciences He received several honorary doctorates, including from the FU Berlin in 2010.
Sixteen of his students became professors in Germany alone, including {{ill|Reinhard Brückner (chemist)|de|Reinhard Brückner (Chemiker)|lt=Reinhard Brückner}}, Johann Gasteiger,[https://pubs.acs.org/doi/pdf/10.1021/ci600240w Johann Gasteiger-Germany’s Pioneer in Chemoinformatics] pubs.acs.org Bernd Giese, {{ill|Herbert Mayr (chemist)|de|Herbert Mayr (Chemiker)|lt=Herbert Mayr}}, Johann Mulzer,[https://scheringstiftung.de/wp-content/uploads/2017/11/1997_Johann-Mulzer-1.pdf Prof. Dr. Johann Mulzer] scheringstiftung.de 21 November 2017 Hans-Ulrich Reissig, {{ill|Jürgen Sauer|de}} and Ivar Karl Ugi.[https://academictree.org/chemistry/tree.php?pid=57594 Chemistry Tree Rolf Huisgen] Academictree chemistry, retrieved 12 February 2018
Personal life
His daughter, mathematician Birge Huisgen-Zimmermann, was born in 1946. He died in Munich on 26 March 2020, aged 99.
Publications
- {{cite book | last1=Huisgen | first1=Rolf | last2=Grashey | first2=Rudolf | last3=Sauer | first3=Jürgen | title=The Alkenes: Vol. 1 (1964) | chapter=Cycloaddition reactions of alkenes | year=1964 | publisher=John Wiley & Sons, Ltd. | publication-place=Chichester, UK | isbn=978-0-470-77104-4 | doi=10.1002/9780470771044.ch11 | pages=739–953}}
- {{cite journal | last=Huisgen | first=Rolf | title=1.3-Dipolare Cycloadditionen Rückschau und Ausblick | journal=Angewandte Chemie | publisher=Wiley | volume=75 | issue=13 | date=7 July 1963 | issn=0044-8249 | doi=10.1002/ange.19630751304 | pages=604–637 | bibcode=1963AngCh..75..604H | language=de}}
- {{cite book | last=Huisgen | first=Rolf | title=The adventure playground of mechanisms and novel reactions | publisher=American Chemical Society | publication-place=Washington, DC | year=1994 | isbn=978-0-8412-1832-1 | oclc=30399911 | page=}}
References
{{reflist|
| refs =
| last = Seeman
| first = Jeffrey I.
| authorlink =Jeffrey I. Seeman
| title = Rolf Huisgen: A Gentleman Scholar with Energy and Passion
| journal = Helvetica Chimica Acta
| volume = 88
| issue = 6
| pages = 1145–1153
| date = 2005
| doi = 10.1002/hlca.200590097
}}
| last = Sustmann
| first = Reiner
| url = https://www.heterocycles.jp/newlibrary/downloads/PDF/00013/40/1
| title = Rolf Huisgen's contribution to organic chemistry, emphasizing 1.3-dipolar cycloadditions
| journal = Heterocycles
| volume = 40
| issue = 1
| date = 1995
| page = 1
| doi = 10.3987/1995-01-0001
| doi-access = free
}}
| url = https://www.chemistryviews.org/details/ezine/11230823/Rolf_Huisgen_1920__2020.html
| title = Rolf Huisgen (1920–2020)
| website = chemistryviews.org
| date = 26 March 2020
| access-date = 27 March 2020
}}
| url = https://www.fu-berlin.de/presse/informationen/fup/2010/fup_10_027/index.html
| title = Ehrendoktorwürde für Chemiker Rolf Huisgen
| website = FU Berlin
| date = 3 February 2010
| language = de
| access-date = 27 March 2010
}}
}}
Literature
- {{cite journal|doi=10.1002/hlca.200590098|title=Rolf Huisgen: Some Highlights of His Contributions to Organic Chemistry|year=2005|last1=Rüchardt|first1=Christoph|last2=Sauer|first2=Jürgen|last3=Sustmann|first3=Reiner|journal=Helvetica Chimica Acta|volume=88|issue=6|pages=1154}}
- {{cite journal|doi=10.1002/hlca.201000209|title=Rolf Huisgen's Profound Adventures in Chemistry|year=2010|last1=Houk|first1=Kendall N.|journal=Helvetica Chimica Acta|volume=93|issue=7|pages=1241–1260}}
External links
{{commonscat}}
- {{DNB portal|119219654}}
- [http://www.scripps.edu/chem/baran/images/grpmtgpdf/Hafensteiner_Oct_04.pdf Rolf Huisgen: The Chemical Adventurer] scripps.edu
- [https://www.cup.lmu.de/de/departments/chemie/personen/prof-dr-rolf-huisgen-em/ Prof. Dr. Rolf Huisgen, em.] Faculty of Chemistry and Pharmacy, LMU Munich
{{Authority control}}
{{DEFAULTSORT:Huisgen, Rolf}}
Category:People from Gerolstein
Category:20th-century German chemists
Category:Ludwig Maximilian University of Munich alumni
Category:Academic staff of the Ludwig Maximilian University of Munich
Category:Foreign associates of the National Academy of Sciences