Rosemary Redfield

{{short description|Microbiologist}}

{{Infobox scientist

| name = Rosie Redfield

| birth_name = Rosemary Jeanne Redfield

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| image = Image_of_Rosie_REdfield.jpg

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| awards = Nature's 10 (2011){{cite journal|last1=Butler|first1=Declan|last2=Callaway|first2=Ewen|last3=Check Hayden|first3=Erika|last4=Cyranoski|first4=David|last5=Hand|first5=Eric|last6=Nosengo|first6=Nicola|last7=Samuel Reich|first7=Eugenie|last8=Tollefson|first8=Jeff|last9=Yahia|first9=Mohammed|title=365 days: Nature's 10|journal=Nature|volume=480|issue=7378|year=2011|pages=437–445|issn=0028-0836|doi=10.1038/480437a|pmid=22193082|bibcode=2011Natur.480..437B|doi-access=free}}

| education =

| alma_mater = Monash University (BSc)
McMaster University (MSc)
Stanford University (PhD)

| thesis_title = Generation of cryptic lambda prophages in Escherichia coli K-12

| thesis_url = https://www.worldcat.org/oclc/{{{16980317}}}

| thesis_year = 1987

| fields = Microbiology
Genetics
DNA
Evolution

| doctoral_advisor = Allan M. Campbell

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| workplaces = University of British Columbia
Harvard University
Johns Hopkins School of Medicine

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| website = {{URL|rrresearch.fieldofscience.com}}

}}

Rosemary Jeanne Redfield is a microbiologist associated with the University of British Columbia{{Google scholar id}} where she worked as a faculty member in the Department of Zoology from 1993 until retiring in 2021.{{Cite web|url=https://www.coursera.org/instructor/~323|title=Coursera - Free Online Courses From Top Universities|website=Coursera|language=en-US|access-date=2016-09-21}}{{Cite web|url=https://www.zoology.ubc.ca/article/dr-rosemary-rosie-redfield-retirement|title="Dr. Rosemary (Rosie) Redfield Retirement"|access-date=2022-07-13}}

Education

Redfield completed her undergraduate degree in biochemistry at Monash University.{{Cite web|url=http://physicsoflivingsystems.org/cdm/bios/|title=Bios {{!}} Cell Decision Making|website=physicsoflivingsystems.org|access-date=2016-09-22}} She continued her education at McMaster University where she completed her MSc in 1980. Her thesis titled, "Methylation and chromatin conformation of adenovirus type 12 DNA sequences in transformed cells," dealt with the chromatin structure and SDNA methylation.{{Cite book|title=Methylation and chromatin conformation of adenovirus type 12 DNA sequences in transformed cells (Order No. MK50873).|last=Redfield|first=Rosemary J.|publisher=McMaster University|year=1980|via=ProQuest Dissertations & Theses Global}} Redfield received her PhD in Biological Sciences from Stanford University under Allan M. Campbell.

Research and career

Redfield completed postdoctoral work at Harvard University with Richard Charles Lewontin and Johns Hopkins School of Medicine with Hamilton O. Smith, an American microbiologist and 1978 Nobel Laureate.{{Cite web|url=http://www.molecularecologist.com/2011/01/looking-to-our-leaders-an-interview-with-rosie-redfield/|title=Looking to our leaders: An interview with Rosie Redfield|date=2011-01-23|language=en-US|access-date=2016-09-26}} She played an early role in the refutation of the GFAJ-1 "arsenic life" results of Felisa Wolfe-Simon.{{Cite journal|last1=Reaves|first1=Marshall Louis|last2=Sinha|first2=Sunita|last3=Rabinowitz|first3=Joshua D.|last4=Kruglyak|first4=Leonid|last5=Redfield|first5=Rosemary J.|date=2012-07-27|title=Absence of Detectable Arsenate in DNA from Arsenate-Grown GFAJ-1 Cells|journal=Science|language=en|volume=337|issue=6093|pages=470–473|doi=10.1126/science.1219861|issn=0036-8075|pmid=22773140|pmc=3845625|bibcode=2012Sci...337..470R|arxiv=1201.6643}}{{Cite news|url=http://www.slate.com/articles/health_and_science/science/2010/12/this_paper_should_not_have_been_published.html|title="This Paper Should Not Have Been Published": Scientists see fatal flaws in the NASA study of arsenic-based life|last=Zimmer|first=Carl|date=2010-12-07|work=Slate|access-date=2017-12-31|language=en-US|issn=1091-2339|author-link=Carl Zimmer}}{{Cite news|url=http://blogs.discovermagazine.com/notrocketscience/2010/12/10/arsenic-bacteria-a-post-mortem-a-review-and-some-navel-gazing/|title=Arsenic bacteria - a post-mortem, a review, and some navel-gazing|last=Yong|first=Ed|date=2010-12-10|work=Not Exactly Rocket Science|access-date=2017-12-31|publisher=Discover Magazine|language=en-US|author-link=Ed Yong}} She joined University of British Colombia as a faculty member in 1993. Rosie's primary research focus has been on the evolution and molecular biology of natural competence in bacteria, or the process through which bacteria take up DNA from their environment. Throughout her career, Redfield championed alternative hypotheses and was not afraid to question generalized assumptions in her field. She notably critiqued a NASA-funded research study by exposing egregious experimental and technical flaws in the research paper. She strongly believes in openness of research and she utilizes her blog as living lab notebook that is open to the public. She retired in 2021.{{Cite web|url=https://www.zoology.ubc.ca/article/dr-rosemary-rosie-redfield-retirement|title="Dr. Rosemary (Rosie) Redfield Retirement"|access-date=2022-07-13}}

= Select publications =

  • {{Cite journal|last1=Boulton|first1=Alan|last2=Myers|first2=Richard S.|last3=Redfield|first3=Rosemary J.|date=1997-07-22|title=The hotspot conversion paradox and the evolution of meiotic recombination|journal=Proceedings of the National Academy of Sciences|language=en|volume=94|issue=15|pages=8058–8063|doi=10.1073/pnas.94.15.8058|issn=0027-8424|pmc=21556|pmid=9223314|bibcode=1997PNAS...94.8058B |doi-access=free }}
  • {{Cite journal|last=Redfield|first=Rosemary J.|date=2001|title=Do bacteria have sex?|url=https://www.nature.com/articles/35084593|journal=Nature Reviews Genetics|language=en|volume=2|issue=8|pages=634–639|doi=10.1038/35084593|pmid=11483988 |s2cid=5465846 |issn=1471-0064}}
  • {{Cite journal|last=Redfield|first=R|date=2002-08-01|title=Is quorum sensing a side effect of diffusion sensing?|url=https://doi.org/10.1016/S0966-842X(02)02400-9|journal=Trends in Microbiology|volume=10|issue=8|pages=365–370|doi=10.1016/s0966-842x(02)02400-9|pmid=12160634|issn=0966-842X}}
  • {{Cite journal|last1=Redfield|first1=Rosemary J.|last2=Cameron|first2=Andrew D. S.|last3=Qian|first3=Qing|last4=Hinds|first4=J.|last5=Ali|first5=Tahir R.|last6=Kroll|first6=J. Simon|last7=Langford|first7=Paul R.|date=2005-04-08|title=A Novel CRP-dependent Regulon Controls Expression of Competence Genes in Haemophilus influenzae|url=https://www.sciencedirect.com/science/article/pii/S0022283605000343|journal=Journal of Molecular Biology|language=en|volume=347|issue=4|pages=735–747|doi=10.1016/j.jmb.2005.01.012|pmid=15769466 |issn=0022-2836}}

Awards

  • CIHR Grant (1999) - Regulation of competence in haemophilus influenzae{{Cite web|url=http://webapps.cihr-irsc.gc.ca/cris/Search?p_language=E&p_version=CRIS|title=Canadian Research Information System|access-date=2017-12-31}}
  • CIHR Grant (2012) - Regulation of CRP-S promoters in H. Influenzae and E. Coli
  • Nominated by Nature as one of Nature's 10 people who mattered in 2011.

References

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