Rotavirus cis-acting replication element

{{Infobox rfam

| Name = Rotavirus cis-acting replication element (CRE)

| image = RF00501.jpg

| width =

| caption = Predicted secondary structure and sequence conservation of Rota_CRE

| Symbol = Rota_CRE

| AltSymbols =

| Rfam = RF00501

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| miRBase_family =

| RNA_type = Cis-reg

| Tax_domain = Viruses

| GO =

| SO = {{SO|0000233}}

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| PDB =

| RefSeq =

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}}

This family represents a rotavirus cis-acting replication element (CRE) found at the 3'-end of rotavirus mRNAs. The family is thought to promote the synthesis of minus strand RNA to form viral dsRNA.{{cite journal | vauthors = Chen D, Barros M, Spencer E, Patton JT | title = Features of the 3'-consensus sequence of rotavirus mRNAs critical to minus strand synthesis | journal = Virology | volume = 282 | issue = 2 | pages = 221–229 | date = April 2001 | pmid = 11289804 | doi = 10.1006/viro.2001.0825 | doi-access = free }}