Route 1 (Paraguay)

{{Short description|Major road in Paraguay}}

{{Unreferenced|date=June 2010}}

{{Expand Spanish|topic=transp|date=January 2025}}

{{Infobox road

|country=PRY

|type=National

|route=01

|image = Ruta PY01 KM 65.jpg

| image_width = 220px

| image_alt =

| image_notes = PY01 sign near the city of Paraguarí.

|alternate_name=Mcal. Francisco Solano López

|maint=

|map=Mapa de la Ruta 1 de Paraguay.svg

|map_notes=PY01 highlighted in red

|length_km= 382

|length_round=

|length_ref=

|established=

|direction_a= North

|terminus_a= Asunción

|junction= Image:R10-PY.svg PY10 in Paraguarí, PI

Image:R18-PY.svg PY18 in Carapeguá, PI

Image:R4-PY.svg PY04 in San Ignacio, MS

Image:R20-PY.svg PY20 in San Patricio, MS

Image:R8-PY.svg PY08 in Coronel Bogado, IT

Image:R6-PY.svg PY06 in Encarnación, IT

|direction_b= South

|terminus_b= Encarnación

|cities=

}}

National Route 1 (officially PY01, in Spanish, Ruta Nacional Número 1, or simply Ruta Uno) is one of the most important and one of the first highways in Paraguay, which runs from the capital city, Asunción to Itapua Department's capital, Encarnación. Crossing the departments of Central, Paraguarí, Misiones and Itapua. It starts on the intersection of Choferes del Chaco and Fernando de la Mora Avenues, known as Cuatro Mojones, and ends at the San Roque González de Santa Cruz Bridge, on the Paraná River, traversing {{convert|382|km|mi|0|abbr=on}}.