S-14506

{{Chembox

| ImageFile = S-14,506 Structure.svg

| ImageSize = 120px

| ImageAlt =

| PIN = 4-Fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide

| OtherNames =

|Section1={{Chembox Identifiers

| IUPHAR_ligand = 24

| CASNo = 135722-25-7

| CASNo_Ref = {{cascite|correct|CAS}}

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = YVO8LE53MI

| PubChem = 131906

| ChemSpiderID = 116528

| SMILES = COC1=CC2=C(C=CC=C2N3CCN(CC3)CCNC(=O)C4=CC=C(C=C4)F)C=C1

| InChI = 1/C24H26FN3O2/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19/h2-10,17H,11-16H2,1H3,(H,26,29)

| InChIKey = IFMQODYDAUKKEN-UHFFFAOYAH

| StdInChI = 1S/C24H26FN3O2/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19/h2-10,17H,11-16H2,1H3,(H,26,29)

| StdInChIKey = IFMQODYDAUKKEN-UHFFFAOYSA-N

| RTECS =

| MeSHName =

| ChEBI = 64101}}

|Section2={{Chembox Properties

| C=24 | H=26 | F=1 | N=3 | O=2

| Appearance =

| Density =

| MeltingPt =

| BoilingPt =

| Solubility = }}

|Section3={{Chembox Hazards

| MainHazards =

| FlashPt =

| AutoignitionPt = }}

}}

S-14,506 is a naphthylpiperazine, a 5-HT1A receptor agonist,{{Cite journal | pmid = 11166326 | date = 2001 | last1 = Milligan | first1 = G. | last2 = Kellett | first2 = E. | last3 = Dacquet | first3 = C. | last4 = Dubreuil | first4 = V. | last5 = Jacoby | first5 = E. | last6 = Millan | first6 = M. J. | last7 = Lavielle | first7 = G. | last8 = Spedding | first8 = M. | title = S 14506: Novel receptor coupling at 5-HT(1A) receptors | journal = Neuropharmacology | volume = 40 | issue = 3 | pages = 334–344 | doi = 10.1016/s0028-3908(00)00162-3 | s2cid = 36060096 }} and a dopamine receptor antagonist.{{Cite journal | pmid = 7698199 | date = 1994 | last1 = Protais | first1 = P. | last2 = Chagraoui | first2 = A. | last3 = Arbaoui | first3 = J. | last4 = Mocaër | first4 = E. | title = Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents | journal = European Journal of Pharmacology | volume = 271 | issue = 1 | pages = 167–177 | doi = 10.1016/0014-2999(94)90277-1 }}