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S100G

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{See also|Calbindin}}

{{Infobox_gene}}

S100 calcium-binding protein G (S100G) is a protein that in humans is encoded by the S100G gene.{{cite journal | vauthors = Howard A, Legon S, Spurr NK, Walters JR | title = Molecular cloning and chromosomal assignment of human calbindin-D9k | journal = Biochem Biophys Res Commun | volume = 185 | issue = 2 | pages = 663–9 | year = 1992 | pmid = 1610358 | doi =10.1016/0006-291X(92)91676-H }}{{cite journal | vauthors = Jeung EB, Krisinger J, Dann JL, Leung PC | title = Molecular cloning of the full-length cDNA encoding the human calbindin-D9k | journal = FEBS Lett | volume = 307 | issue = 2 | pages = 224–8 |date=Sep 1992 | pmid = 1379540 | doi =10.1016/0014-5793(92)80772-9 | s2cid = 27787157 | doi-access = free }}{{cite web | title = Entrez Gene: S100G S100 calcium binding protein G| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=795}}

This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles.

References

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Further reading

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  • {{cite journal | author=Balmain N |title=Calbindin-D9k. A vitamin-D-dependent, calcium-binding protein in mineralized tissues |journal=Clin. Orthop. Relat. Res. |issue= 265 |pages= 265–76 |year= 1991 |pmid= 2009668 }}
  • {{cite journal | vauthors=Fleet JC, Hock JM |title=Identification of osteocalcin mRNA in nonosteoid tissue of rats and humans by reverse transcription-polymerase chain reaction |journal=J. Bone Miner. Res. |volume=9 |issue= 10 |pages= 1565–73 |year= 1995 |pmid= 7817802 |doi=10.1002/jbmr.5650091009 |s2cid=1687493 }}
  • {{cite journal | vauthors=Jeung EB, Leung PC, Krisinger J |title=The human calbindin-D9k gene. Complete structure and implications on steroid hormone regulation |journal=J. Mol. Biol. |volume=235 |issue= 4 |pages= 1231–8 |year= 1994 |pmid= 8308886 |doi= 10.1006/jmbi.1994.1076 }}
  • {{cite journal |vauthors=Barley NF, Prathalingam SR, Zhi P, etal |title=Factors involved in the duodenal expression of the human calbindin-D9k gene |journal=Biochem. J. |volume=341 |issue= 3|pages= 491–500 |year= 1999 |pmid= 10417310 |doi=10.1042/0264-6021:3410491 | pmc=1220384 }}
  • {{cite journal | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA Cloning Using In Vitro Site-Specific Recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000 | pmc=310948 }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Wang L, Klopot A, Freund JN, etal |title=Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1α |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=287 |issue= 5 |pages= G943–53 |year= 2004 |pmid= 15217781 |doi= 10.1152/ajpgi.00121.2004 | pmc=2701355 }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
  • {{cite journal |vauthors=Ross MT, Grafham DV, Coffey AJ, etal |title=The DNA sequence of the human X chromosome |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 | pmc=2665286 |bibcode=2005Natur.434..325R }}

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{{Calcium-binding proteins}}

Category:S100 proteins