SAE

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• Selective area epitaxy, local growth of epitaxial layer through a patterned dielectric mask deposited on a semiconductor substrate
• Sepsis-associated encephalopathy, neurological complications of sepsis
• Serious adverse event, in a clinical trial
• Simultaneous Authentication of Equals, a password authentication protocol in computer networking
• Sparse autoencoder, a class of text encoders in machine learning
• Subcortical arteriosclerotic encephalopathy, a disease
• Sum of absolute errors, in mathematics
• Supervised agricultural experience
• System Architecture Evolution, the core network architecture of 3GPP's LTE wireless communication standard

Units named after the Society of Automotive Engineers (see below):

• SAE, several units of measurement of power; See Horsepower
• SAE viscosity number, of motor oils
• SAE steel grades
• SAE fastener
• SAE thread
• United States customary units, e.g. inches and miles rather than millimeters and kilometers

• South African English, the first-language dialects of English spoken by South Africans
• Standard Average European, a sprachbund consisting of the major part of the Indo-European languages
• Standard American English (disambiguation), the standardized form of written American English
• Southern American English

• SAE Institute (formerly the School of Audio Engineering), a private college founded in 1976
• SAE Online (formerly SAE Graduate college), distance learning programs run by SAE Institute
• SAE International (originally the Society of Automotive Engineers), a US-based, global professional association and standards developing organization for engineering professionals in various industries
• SAE Renewables (formerly SIMEC Atlantis Energy) a renewable energy company incorporated in Singapore, but with headquarters in Edinburgh
• SAE – World Council of Hellenes Abroad, the main body representing people of Greek ethnic descent, the Greek Diaspora (Omogeneia) living outside the boundaries of the Greek state
• {{lang|pt|Secretaria de Assuntos Estratégicos}}, the Brazilian Intelligence Agency
• Sigma Alpha Epsilon, a fraternity
• Society of Accountants in Edinburgh, founded in 1853, a predecessor of the Institute of Chartered Accountants of Scotland
• Soviet Antarctic Expedition, part of the Arctic and Antarctic Research Institute of the Soviet Committee on Antarctic Research of the Academy of Sciences of the USSR
• Stichting Academisch Erfgoed, a Dutch organization

• Sae, Harju County, village in Kose Parish, Harju County, Estonia
• Sae, Lääne-Viru County, village in Vinni Parish, Lääne-Viru County, Estonia
• Shah Alam Expressway, an expressway in Klang Valley, Malaysia
• Sae Island, an island within the Western Islands of the Bismarck Archipelago, Papua New Guinea

• Sae (given name), a feminine Japanese given name
• Sale railway station, Victoria
• Société anonyme égyptienne ("Egyptian Anonymous Society"), Egyptian variant of S.A.
• Stamped addressed envelope

• Sexual assault evidence collection kit (SAECK), in forensics

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