SCN2B
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Sodium channel subunit beta-2 is a protein that in humans is encoded by the SCN2B gene.{{cite journal | vauthors = Plummer NW, Meisler MH | title = Evolution and diversity of mammalian sodium channel genes | journal = Genomics | volume = 57 | issue = 2 | pages = 323–31 |date=May 1999 | pmid = 10198179 | doi = 10.1006/geno.1998.5735 }}{{cite web | title = Entrez Gene: SCN2B sodium channel, voltage-gated, type II, beta| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6327}}
See also
References
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Further reading
{{refbegin | 2}}
- {{cite journal | vauthors=Hartshorne RP, Catterall WA |title=The sodium channel from rat brain. Purification and subunit composition. |journal=J. Biol. Chem. |volume=259 |issue= 3 |pages= 1667–75 |year= 1984 |doi=10.1016/S0021-9258(17)43460-0 |pmid= 6319405 |doi-access=free }}
- {{cite journal |vauthors=Adams MD, Kerlavage AR, Fleischmann RD, etal |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3–174 |year= 1995 |pmid= 7566098 |url=http://www.columbia.edu/itc/biology/pollack/w4065/client_edit/readings/nature377_3.pdf }}
- {{cite journal |vauthors=Isom LL, Ragsdale DS, De Jongh KS, etal |title=Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif |journal=Cell |volume=83 |issue= 3 |pages= 433–42 |year= 1996 |pmid= 8521473 |doi=10.1016/0092-8674(95)90121-3 |s2cid=13998841 |doi-access=free }}
- {{cite journal |vauthors=Eubanks J, Srinivasan J, Dinulos MB, etal |title=Structure and chromosomal localization of the beta2 subunit of the human brain sodium channel |journal=NeuroReport |volume=8 |issue= 12 |pages= 2775–9 |year= 1997 |pmid= 9295116 |doi=10.1097/00001756-199708180-00025 |s2cid=21051920 }}
- {{cite journal |vauthors=Bolino A, Seri M, Caroli F, etal |title=Exclusion of the SCN2B gene as candidate for CMT4B |journal=Eur. J. Hum. Genet. |volume=6 |issue= 6 |pages= 629–34 |year= 1999 |pmid= 9887383 |doi= 10.1038/sj.ejhg.5200220 |doi-access= free }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Kim DY, Ingano LA, Carey BW, etal |title=Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration |journal=J. Biol. Chem. |volume=280 |issue= 24 |pages= 23251–61 |year= 2005 |pmid= 15833746 |doi= 10.1074/jbc.M412938200 |doi-access= free }}
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External links
- {{MeshName|SCN2B+protein,+human}}
- {{PDBe-KB2|O60939|Sodium channel subunit beta-2}}
{{NLM content}}
{{Ion channels|g2}}
{{membrane-protein-stub}}