SEC24A
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox gene}}
SEC24 family, member A (S. cerevisiae) is a protein that in humans is encoded by the SEC24A gene.{{cite web | title = SEC24 family, member A (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/gene/10802| access-date = 2011-12-05}} The protein belongs to a protein family that are homologous to yeast Sec24.{{cite journal | vauthors = Tang BL, Kausalya J, Low DY, Lock ML, Hong W | title = A family of mammalian proteins homologous to yeast Sec24p | journal = Biochemical and Biophysical Research Communications | volume = 258 | issue = 3 | pages = 679–84 | date = May 1999 | pmid = 10329445 | doi = 10.1006/bbrc.1999.0574 }} It is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum.
References
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Further reading
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- {{cite journal | vauthors = Mancias JD, Goldberg J | title = The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope | journal = Molecular Cell | volume = 26 | issue = 3 | pages = 403–14 | date = May 2007 | pmid = 17499046 | doi = 10.1016/j.molcel.2007.03.017 | doi-access = free }}
- {{cite journal | vauthors = Wendeler MW, Paccaud JP, Hauri HP | title = Role of Sec24 isoforms in selective export of membrane proteins from the endoplasmic reticulum | journal = EMBO Reports | volume = 8 | issue = 3 | pages = 258–64 | date = March 2007 | pmid = 17255961 | pmc = 1808030 | doi = 10.1038/sj.embor.7400893 }}
- {{cite journal | vauthors = Kirchhausen T | title = Three ways to make a vesicle | journal = Nature Reviews. Molecular Cell Biology | volume = 1 | issue = 3 | pages = 187–98 | date = December 2000 | pmid = 11252894 | doi = 10.1038/35043117 | s2cid = 205011168 }}
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External links
- [https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/O95486 PDBe-KB] provides an overview of all the structure information available in the PDB for Human Protein transport protein Sec24A
{{Vesicular transport proteins}}
Category:Genes mutated in mice
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