SEPT10

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Septin 10 is a protein that in humans is encoded by the SEPT10 gene.{{cite web | title = Entrez Gene: Septin 10 | url = https://www.ncbi.nlm.nih.gov/gene/151011 }}

Function

This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternative splicing results in multiple transcript variants.

References

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Further reading

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  • {{cite journal | vauthors = Sui L, Zhang W, Liu Q, Chen T, Li N, Wan T, Yu M, Cao X | title = Cloning and functional characterization of human septin 10, a novel member of septin family cloned from dendritic cells | journal = Biochemical and Biophysical Research Communications | volume = 304 | issue = 2 | pages = 393–8 | date = May 2003 | pmid = 12711328 | doi = 10.1016/s0006-291x(03)00601-6 }}
  • {{cite journal | vauthors = Benedetti D, Bomben R, Dal-Bo M, Marconi D, Zucchetto A, Degan M, Forconi F, Del-Poeta G, Gaidano G, Gattei V | title = Are surrogates of IGHV gene mutational status useful in B-cell chronic lymphocytic leukemia? The example of Septin-10 | journal = Leukemia | volume = 22 | issue = 1 | pages = 224–6 | date = January 2008 | pmid = 17657217 | doi = 10.1038/sj.leu.2404867 | doi-access = }}
  • {{cite journal | vauthors = Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M | title = Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen | journal = Cancer Science | volume = 103 | issue = 4 | pages = 821–7 | date = April 2012 | pmid = 22320903 | doi = 10.1111/j.1349-7006.2012.02221.x | pmc = 7659246 | s2cid = 3456503 | doi-access = free }}

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