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SERPINB6

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Serpin B6 is a protein that in humans is encoded by the SERPINB6 gene.{{cite journal |vauthors=Coughlin P, Sun J, Cerruti L, Salem HH, Bird P | title = Cloning and molecular characterization of a human intracellular serine proteinase inhibitor | journal = Proc Natl Acad Sci U S A | volume = 90 | issue = 20 | pages = 9417–21 |date=Nov 1993 | pmid = 8415716 | pmc = 47579 | doi =10.1073/pnas.90.20.9417 | bibcode = 1993PNAS...90.9417C | doi-access = free }}{{cite journal |vauthors=Sun J, Stephens R, Mirza G, Kanai H, Ragoussis J, Bird PI | title = A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes | journal = Cytogenet Cell Genet | volume = 82 | issue = 3–4 | pages = 273–7 |date=Feb 1999 | pmid = 9858835 | doi =10.1159/000015118 | s2cid = 23659776 }}{{cite web | title = Entrez Gene: SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5269}}

See also

References

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Further reading

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  • {{cite journal |vauthors=Sun J, Coughlin P, Salem HH, Bird P |title=Production and characterization of recombinant human proteinase inhibitor 6 expressed in Pichia pastoris |journal=Biochim. Biophys. Acta |volume=1252 |issue= 1 |pages= 28–34 |year= 1995 |pmid= 7548163 |doi=10.1016/0167-4838(95)00108-7 }}
  • {{cite journal | author=Coughlin P |title=Chromosomal mapping of the human proteinase inhibitor 6 (PI6) gene to 6p25 by fluorescence in situ hybridization |journal=Genomics |volume=26 |issue= 2 |pages= 431–3 |year= 1995 |pmid= 7601482 |doi=10.1016/0888-7543(95)80240-M |name-list-style=vanc| author2=Nicholl J | author3=Sun J | display-authors=3 | last4=Salem | first4=Hatem | last5=Bird | first5=Phillip | last6=Sutherland | first6=Grant R. }}
  • {{cite journal | author=Morgenstern KA |title=Complementary DNA cloning and kinetic characterization of a novel intracellular serine proteinase inhibitor: mechanism of action with trypsin and factor Xa as model proteinases |journal=Biochemistry |volume=33 |issue= 11 |pages= 3432–41 |year= 1994 |pmid= 8136380 |doi=10.1021/bi00177a037 |name-list-style=vanc| author2=Sprecher C | author3=Holth L | display-authors=3 | last4=Foster | first4=Donald | last5=Grant | first5=Francis J. | last6=Ching | first6=Andrew | last7=Kisiel | first7=Walter }}
  • {{cite journal | author=Morgenstern KA |title=Isolation and characterization of an intracellular serine proteinase inhibitor from a monkey kidney epithelial cell line |journal=J. Biol. Chem. |volume=268 |issue= 29 |pages= 21560–8 |year= 1993 |pmid= 8408007 |name-list-style=vanc| author2=Henzel WJ | author3=Baker JB | display-authors=3 | last4=Wong | first4=S | last5=Pastuszyn | first5=A | last6=Kisiel | first6=W |doi=10.1016/S0021-9258(20)80578-X |doi-access=free }}
  • {{cite journal |vauthors=Coughlin PB, Tetaz T, Salem HH |title=Identification and purification of a novel serine proteinase inhibitor |journal=J. Biol. Chem. |volume=268 |issue= 13 |pages= 9541–7 |year= 1993 |doi=10.1016/S0021-9258(18)98385-7 |pmid= 8486644 |doi-access=free }}
  • {{cite journal |vauthors=Riewald M, Morgenstern KA, Schleef RR |title=Identification and characterization of the cytoplasmic antiproteinase (CAP) in human platelets. Evidence for the interaction of CAP with endogenous platelet proteins |journal=J. Biol. Chem. |volume=271 |issue= 12 |pages= 7160–7 |year= 1996 |pmid= 8636153 |doi= 10.1074/jbc.271.12.7160|doi-access=free }}
  • {{cite journal |vauthors=Riewald M, Schleef RR |title=Human cytoplasmic antiproteinase neutralizes rapidly and efficiently chymotrypsin and trypsin-like proteases utilizing distinct reactive site residues |journal=J. Biol. Chem. |volume=271 |issue= 24 |pages= 14526–32 |year= 1996 |pmid= 8662739 |doi=10.1074/jbc.271.24.14526 |doi-access=free }}
  • {{cite journal | author=Scott FL |title=Proteinase inhibitor 6 (PI-6) expression in human skin: induction of PI-6 and a PI-6/proteinase complex during keratinocyte differentiation |journal=Exp. Cell Res. |volume=245 |issue= 2 |pages= 263–71 |year= 1999 |pmid= 9851866 |doi= 10.1006/excr.1998.4241 |name-list-style=vanc| author2=Paddle-Ledinek JE | author3=Cerruti L | display-authors=3 | last4=Coughlin | first4=PB | last5=Salem | first5=HH | last6=Bird | first6=PI }}
  • {{cite journal | author=Mikolajczyk SD |title=Identification of a novel complex between human kallikrein 2 and protease inhibitor-6 in prostate cancer tissue |journal=Cancer Res. |volume=59 |issue= 16 |pages= 3927–30 |year= 1999 |pmid= 10463585 |name-list-style=vanc| author2=Millar LS | author3=Marker KM | display-authors=3 | last4=Rittenhouse | first4=HG | last5=Wolfert | first5=RL | last6=Marks | first6=LS | last7=Charlesworth | first7=MC | last8=Tindall | first8=DJ }}
  • {{cite journal | author=Saedi MS |title=Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells |journal=Int. J. Cancer |volume=94 |issue= 4 |pages= 558–63 |year= 2002 |pmid= 11745444 |doi=10.1002/ijc.1501 |name-list-style=vanc| author2=Zhu Z | author3=Marker K | display-authors=3 | last4=Liu | first4=Ru-Shya | last5=Carpenter | first5=Philip M. | last6=Rittenhouse | first6=Harry | last7=Mikolajczyk | first7=Stephen D. |s2cid=2826757 | doi-access=free }}
  • {{cite journal | author=Wistow G |title=Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants |journal=Mol. Vis. |volume=8 |pages= 171–84 |year= 2002 |pmid= 12107413 |name-list-style=vanc| author2=Bernstein SL | author3=Wyatt MK | display-authors=3 | last4=Behal | first4=A | last5=Touchman | first5=JW | last6=Bouffard | first6=G | last7=Smith | first7=D | last8=Peterson | first8=K }}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | author=Strik MC |title=Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers |journal=Blood |volume=103 |issue= 7 |pages= 2710–7 |year= 2004 |pmid= 14670919 |doi= 10.1182/blood-2003-08-2981 |name-list-style=vanc| author2=Wolbink A | author3=Wouters D | display-authors=3 | last4=Bladergroen | first4=BA | last5=Verlaan | first5=AR | last6=Van Houdt | first6=IS | last7=Hijlkema | first7=S | last8=Hack | first8=CE | last9=Kummer | first9=JA | doi-access=free }}
  • {{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-style=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki | doi-access=free }}
  • {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-style=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
  • {{cite journal | author=Charron Y |title=Expression of serpinb6 serpins in germ and somatic cells of mouse gonads |journal=Mol. Reprod. Dev. |volume=73 |issue= 1 |pages= 9–19 |year= 2006 |pmid= 16175637 |doi= 10.1002/mrd.20385 |name-list-style=vanc| author2=Madani R | author3=Nef S | display-authors=3 | last4=Combepine | first4=Chantal | last5=Govin | first5=Jérôme | last6=Khochbin | first6=Saadi | last7=Vassalli | first7=Jean-Dominique |s2cid=42438203 }}
  • {{cite journal | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |name-list-style=vanc| author2=Venkatesan K | author3=Hao T | display-authors=3 | last4=Hirozane-Kishikawa | first4=Tomoko | last5=Dricot | first5=Amélie | last6=Li | first6=Ning | last7=Berriz | first7=Gabriel F. | last8=Gibbons | first8=Francis D. | last9=Dreze | first9=Matija |bibcode=2005Natur.437.1173R |s2cid=4427026 }}

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External links

  • The MEROPS online database for peptidases and their inhibitors: [http://merops.sanger.ac.uk/cgi-bin/merops.cgi?id=I04.011 I04.011]
  • {{MeshName|SERPINB6+protein,+human}}

{{Serpins}}

Category:Serine protease inhibitors

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