SFRS3

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Splicing factor, arginine/serine-rich 3 is a protein that in humans is encoded by the SFRS3 gene.{{cite journal |author1=Zahler AM |author2=Lane WS |author3=Stolk JA |author4=Roth MB | title = SR proteins: a conserved family of pre-mRNA splicing factors | journal = Genes Dev | volume = 6 | issue = 5 | pages = 837–47 |date=Jun 1992 | pmid = 1577277 | doi =10.1101/gad.6.5.837 | doi-access =free }}{{cite web | title = Entrez Gene: SFRS3 splicing factor, arginine/serine-rich 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6428}}

Browser View

[http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg18&knownGene=pack&hgFind.matches=uc003omj.1, UCSC Genome Browser View]

[http://genome.ucsc.edu/cgi-bin/hgGene?hgg_gene=uc003omj.1&hgg_prot=P84103&hgg_type=knownGene&db=hg18, UCSC Gene details page]

Interactions

SFRS3 has been shown to interact with RBM7.{{cite journal |last=Guo |first=Taylor B |author2=Boros Laszlo G |author3=Chan Kam C |author4=Hikim Amiya P Sinha |author5=Hudson Alan P |author6=Swerdloff Ronald S |author7=Mitchell Aaron P |author8=Salameh Wael A |year=2003|title=Spermatogenetic expression of RNA-binding motif protein 7, a protein that interacts with splicing factors |journal=J. Androl. |volume=24 |issue=2 |pages=204–14 | issn = 0196-3635| pmid = 12634307 | doi=10.1002/j.1939-4640.2003.tb02664.x}}

References

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Further reading

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  • {{cite journal |author1=Ayane M |author2=Preuss U |author3=Köhler G |author4=Nielsen PJ |title=A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs. |journal=Nucleic Acids Res. |volume=19 |issue= 6 |pages= 1273–8 |year= 1991 |pmid= 2030943 |doi=10.1093/nar/19.6.1273 | pmc=333853 }}
  • {{cite journal |author1=Gui JF |author2=Lane WS |author3=Fu XD |title=A serine kinase regulates intracellular localization of splicing factors in the cell cycle. |journal=Nature |volume=369 |issue=6482 |pages=678–82 |year=1994 |pmid=8208298 |doi=10.1038/369678a0 |bibcode=1994Natur.369..678G |s2cid=4275539 |url=http://ir.ihb.ac.cn/handle/152342/10318 |access-date=2019-12-14 |archive-date=2020-12-03 |archive-url=https://web.archive.org/web/20201203094718/http://ir.ihb.ac.cn/handle/152342/10318 |url-status=dead |url-access=subscription }}
  • {{cite journal |author1=Cáceres JF |author2=Screaton GR |author3=Krainer AR |title=A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm. |journal=Genes Dev. |volume=12 |issue= 1 |pages= 55–66 |year= 1998 |pmid= 9420331 |doi=10.1101/gad.12.1.55 | pmc=316398 }}
  • {{cite journal |author1=Zhang WJ |author2=Wu JY |title=Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing. |journal=Mol. Cell. Biol. |volume=18 |issue= 2 |pages= 676–84 |year= 1998 |pmid= 9447963 |doi= 10.1128/MCB.18.2.676| pmc=108778 }}
  • {{cite journal |vauthors=Tripodis N, Mason R, Humphray SJ, etal |title=Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex. |journal=Genome Res. |volume=8 |issue= 6 |pages= 631–43 |year= 1999 |pmid= 9647638 |doi= 10.1101/gr.8.6.631| pmc=310739 }}
  • {{cite journal |vauthors=Papoutsopoulou S, Nikolakaki E, Chalepakis G, etal |title=SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1. |journal=Nucleic Acids Res. |volume=27 |issue= 14 |pages= 2972–80 |year= 1999 |pmid= 10390541 |doi=10.1093/nar/27.14.2972 | pmc=148514 }}
  • {{cite journal |author1=Barnard DC |author2=Patton JG |title=Identification and characterization of a novel serine-arginine-rich splicing regulatory protein. |journal=Mol. Cell. Biol. |volume=20 |issue= 9 |pages= 3049–57 |year= 2000 |pmid= 10757789 |doi=10.1128/MCB.20.9.3049-3057.2000 | pmc=85584 }}
  • {{cite journal |vauthors=Shnyreva M, Schullery DS, Suzuki H, etal |title=Interaction of two multifunctional proteins. Heterogeneous nuclear ribonucleoprotein K and Y-box-binding protein. |journal=J. Biol. Chem. |volume=275 |issue= 20 |pages= 15498–503 |year= 2000 |pmid= 10809782 |doi=10.1074/jbc.275.20.15498 |doi-access=free }}
  • {{cite journal |vauthors=Elliott DJ, Bourgeois CF, Klink A, etal |title=A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 11 |pages= 5717–22 |year= 2000 |pmid= 10823932 |doi=10.1073/pnas.97.11.5717 | pmc=18499 |bibcode=2000PNAS...97.5717E |doi-access=free }}
  • {{cite journal |author1=Huang Y |author2=Steitz JA |title=Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA. |journal=Mol. Cell |volume=7 |issue= 4 |pages= 899–905 |year= 2001 |pmid= 11336712 |doi=10.1016/S1097-2765(01)00233-7 |doi-access=free }}
  • {{cite journal |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9 |s2cid=14132033 |doi-access=free }}
  • {{cite journal |author1=Barnard DC |author2=Li J |author3=Peng R |author4=Patton JG |title=Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins. |journal=RNA |volume=8 |issue= 4 |pages= 526–33 |year= 2002 |pmid= 11991645 |doi=10.1017/S1355838202029928 | pmc=1370273 }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Guo TB, Boros LG, Chan KC, etal |title=Spermatogenetic expression of RNA-binding motif protein 7, a protein that interacts with splicing factors. |journal=J. Androl. |volume=24 |issue= 2 |pages= 204–14 |year= 2003 |pmid= 12634307 |doi= 10.1002/j.1939-4640.2003.tb02664.x}}
  • {{cite journal |vauthors=Tai HH, Geisterfer M, Bell JC, etal |title=CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins. |journal=Biochem. Biophys. Res. Commun. |volume=308 |issue= 1 |pages= 170–6 |year= 2003 |pmid= 12890497 |doi=10.1016/S0006-291X(03)01354-8 }}
  • {{cite journal |vauthors=Li J, Hawkins IC, Harvey CD, etal |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437–47 |year= 2003 |pmid= 14559993 |doi=10.1128/MCB.23.21.7437-7447.2003 | pmc=207616 }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
  • {{cite journal |vauthors= Dettwiler S, Aringhieri C, Cardinale S, etal |title= Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. |journal= J. Biol. Chem. |volume= 279 |issue= 34 |pages= 35788–97 |year= 2005 |pmid= 15169763 |doi= 10.1074/jbc.M403927200 |s2cid= 39752996 |url= https://boa.unimib.it/bitstream/10281/4454/3/Dettwiler_et_al_Rev.pdf |doi-access= free }}
  • {{cite journal |author1=Lehner B |author2=Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 | pmc=442147 }}

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