SFRS6

The protein encoded by this gene is involved in mRNA splicing and may play a role in site selection in alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.

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• {{cite journal | vauthors = Zahler AM, Lane WS, Stolk JA, Roth MB | title = SR proteins: a conserved family of pre-mRNA splicing factors | journal = Genes & Development | volume = 6 | issue = 5 | pages = 837–47 | date = May 1992 | pmid = 1577277 | doi = 10.1101/gad.6.5.837 | doi-access = free }}
• {{cite journal | vauthors = Ramchatesingh J, Zahler AM, Neugebauer KM, Roth MB, Cooper TA | title = A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer | journal = Molecular and Cellular Biology | volume = 15 | issue = 9 | pages = 4898–907 | date = September 1995 | pmid = 7651409 | pmc = 230736 | doi = 10.1128/MCB.15.9.4898}}
• {{cite journal | vauthors = Gui JF, Lane WS, Fu XD | title = A serine kinase regulates intracellular localization of splicing factors in the cell cycle | journal = Nature | volume = 369 | issue = 6482 | pages = 678–82 | date = June 1994 | pmid = 8208298 | doi = 10.1038/369678a0 | bibcode = 1994Natur.369..678G | s2cid = 4275539 | url = http://ir.ihb.ac.cn/handle/152342/10318 | access-date = 2019-12-11 | archive-date = 2020-12-03 | archive-url = https://web.archive.org/web/20201203094718/http://ir.ihb.ac.cn/handle/152342/10318 | url-status = dead }}
• {{cite journal | vauthors = Nagel RJ, Lancaster AM, Zahler AM | title = Specific binding of an exonic splicing enhancer by the pre-mRNA splicing factor SRp55 | journal = RNA | volume = 4 | issue = 1 | pages = 11–23 | date = January 1998 | pmid = 9436904 | pmc = 1369592 }}
• {{cite journal | vauthors = Liu HX, Zhang M, Krainer AR | title = Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins | journal = Genes & Development | volume = 12 | issue = 13 | pages = 1998–2012 | date = July 1998 | pmid = 9649504 | pmc = 316967 | doi = 10.1101/gad.12.13.1998 }}
• {{cite journal | vauthors = Lemaire R, Winne A, Sarkissian M, Lafyatis R | title = SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation | journal = European Journal of Immunology | volume = 29 | issue = 3 | pages = 823–37 | date = March 1999 | pmid = 10092085 | doi = 10.1002/(SICI)1521-4141(199903)29:03<823::AID-IMMU823>3.0.CO;2-C | s2cid = 23297953 | doi-access = free }}
• {{cite journal | vauthors = Paillard F | title = A novel soluble chimera for the treatment of familial hypercholesterolemia | journal = Human Gene Therapy | volume = 10 | issue = 7 | pages = 1093–4 | date = May 1999 | pmid = 10340541 | doi = 10.1089/10430349950018085 }}
• {{cite journal | vauthors = Barnard DC, Patton JG | title = Identification and characterization of a novel serine-arginine-rich splicing regulatory protein | journal = Molecular and Cellular Biology | volume = 20 | issue = 9 | pages = 3049–57 | date = May 2000 | pmid = 10757789 | pmc = 85584 | doi = 10.1128/MCB.20.9.3049-3057.2000 }}
• {{cite journal | vauthors = Monsalve M, Wu Z, Adelmant G, Puigserver P, Fan M, Spiegelman BM | title = Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1 | journal = Molecular Cell | volume = 6 | issue = 2 | pages = 307–16 | date = August 2000 | pmid = 10983978 | doi = 10.1016/S1097-2765(00)00031-9 | doi-access = free }}
• {{cite journal | vauthors = Fossey SC, Mychaleckyj JC, Pendleton JK, Snyder JR, Bensen JT, Hirakawa S, Rich SS, Freedman BI, Bowden DW | title = A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20 | journal = Genomics | volume = 76 | issue = 1–3 | pages = 45–57 | date = August 2001 | pmid = 11549316 | doi = 10.1006/geno.2001.6584 }}
• {{cite journal | vauthors = Tran Q, Coleman TP, Roesser JR | title = Human transformer 2beta and SRp55 interact with a calcitonin-specific splice enhancer | journal = Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | volume = 1625 | issue = 2 | pages = 141–52 | date = January 2003 | pmid = 12531473 | doi = 10.1016/S0167-4781(02)00600-0 }}
• {{cite journal | vauthors = Tran Q, Roesser JR | title = SRp55 is a regulator of calcitonin/CGRP alternative RNA splicing | journal = Biochemistry | volume = 42 | issue = 4 | pages = 951–7 | date = February 2003 | pmid = 12549914 | doi = 10.1021/bi026753a }}
• {{cite journal | vauthors = Lai MC, Lin RI, Tarn WY | title = Differential effects of hyperphosphorylation on splicing factor SRp55 | journal = The Biochemical Journal | volume = 371 | issue = Pt 3 | pages = 937–45 | date = May 2003 | pmid = 12549978 | pmc = 1223332 | doi = 10.1042/BJ20021827 }}
• {{cite journal | vauthors = Pind MT, Watson PH | title = SR protein expression and CD44 splicing pattern in human breast tumours | journal = Breast Cancer Research and Treatment | volume = 79 | issue = 1 | pages = 75–82 | date = May 2003 | pmid = 12779084 | doi = 10.1023/A:1023338718974 | s2cid = 24657578 }}
• {{cite journal | vauthors = Li J, Hawkins IC, Harvey CD, Jennings JL, Link AJ, Patton JG | title = Regulation of alternative splicing by SRrp86 and its interacting proteins | journal = Molecular and Cellular Biology | volume = 23 | issue = 21 | pages = 7437–47 | date = November 2003 | pmid = 14559993 | pmc = 207616 | doi = 10.1128/MCB.23.21.7437-7447.2003 }}
• {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = August 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 | bibcode = 2004PNAS..10112130B | doi-access = free }}

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