SFRS9
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Splicing factor, arginine/serine-rich 9, also known as SFRS9, is a human gene encoding an SR protein involved in splice site selection in alternative splicing.{{cite web | title = Entrez Gene: SFRS9 splicing factor, arginine/serine-rich 9| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8683| accessdate = }}
Interactions
SFRS9 has been shown to interact with Y box binding protein 1{{cite journal |last=Raffetseder |first=Ute |author2=Frye Björn |author3=Rauen Thomas |author4=Jürchott Karsten |author5=Royer Hans-Dieter |author6=Jansen Petra Lynen |author7=Mertens Peter R |date=May 2003 |title=Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection |journal=J. Biol. Chem. |volume=278 |issue=20 |pages=18241–8 | issn = 0021-9258| pmid = 12604611 |doi = 10.1074/jbc.M212518200 |doi-access=free }} and NOL3.{{cite journal |doi=10.1074/jbc.274.16.10951 |last=Stoss |first=O |author2=Schwaiger F W |author3=Cooper T A |author4=Stamm S |date=Apr 1999 |title=Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c |journal=J. Biol. Chem. |volume=274 |issue=16 |pages=10951–62 | issn = 0021-9258| pmid = 10196175 |doi-access=free }}
References
{{reflist}}
Further reading
{{refbegin | 2}}
- {{cite journal |vauthors=Screaton GR, Cáceres JF, Mayeda A, etal |title=Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. |journal=EMBO J. |volume=14 |issue= 17 |pages= 4336–49 |year= 1995 |pmid= 7556075 |doi= 10.1002/j.1460-2075.1995.tb00108.x| pmc=394518 }}
- {{cite journal |vauthors=Nayler O, Strätling W, Bourquin JP, etal |title=SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements. |journal=Nucleic Acids Res. |volume=26 |issue= 15 |pages= 3542–9 |year= 1998 |pmid= 9671816 |doi=10.1093/nar/26.15.3542 | pmc=147731 }}
- {{cite journal |author1=Yuan Y |author2=Li DM |author3=Sun H |title=PIR1, a novel phosphatase that exhibits high affinity to RNA . ribonucleoprotein complexes. |journal=J. Biol. Chem. |volume=273 |issue= 32 |pages= 20347–53 |year= 1998 |pmid= 9685386 |doi=10.1074/jbc.273.32.20347 |doi-access=free }}
- {{cite journal |vauthors=Petersen-Mahrt SK, Estmer C, Ohrmalm C, etal |title=The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation. |journal=EMBO J. |volume=18 |issue= 4 |pages= 1014–24 |year= 1999 |pmid= 10022843 |doi= 10.1093/emboj/18.4.1014 | pmc=1171193 }}
- {{cite journal |author1=Stoss O |author2=Schwaiger FW |author3=Cooper TA |author4=Stamm S |title=Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c. |journal=J. Biol. Chem. |volume=274 |issue= 16 |pages= 10951–62 |year= 1999 |pmid= 10196175 |doi=10.1074/jbc.274.16.10951 |doi-access=free }}
- {{cite journal |vauthors=Elliott DJ, Bourgeois CF, Klink A, etal |title=A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 11 |pages= 5717–22 |year= 2000 |pmid= 10823932 |doi=10.1073/pnas.97.11.5717 | pmc=18499 |bibcode=2000PNAS...97.5717E |doi-access=free }}
- {{cite journal |vauthors=Stoss O, Olbrich M, Hartmann AM, etal |title=The STAR/GSG family protein rSLM-2 regulates the selection of alternative splice sites. |journal=J. Biol. Chem. |volume=276 |issue= 12 |pages= 8665–73 |year= 2001 |pmid= 11118435 |doi= 10.1074/jbc.M006851200 |doi-access= free }}
- {{cite journal |vauthors=Denegri M, Chiodi I, Corioni M, etal |title=Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors. |journal=Mol. Biol. Cell |volume=12 |issue= 11 |pages= 3502–14 |year= 2002 |pmid= 11694584 |doi= 10.1091/mbc.12.11.3502| pmc=60271 }}
- {{cite journal |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9 |s2cid=14132033 |doi-access=free }}
- {{cite journal |vauthors=Young PJ, DiDonato CJ, Hu D, etal |title=SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. |journal=Hum. Mol. Genet. |volume=11 |issue= 5 |pages= 577–87 |year= 2002 |pmid= 11875052 |doi=10.1093/hmg/11.5.577 |doi-access=free }}
- {{cite journal |author1=Simard MJ |author2=Chabot B |title=SRp30c is a repressor of 3' splice site utilization. |journal=Mol. Cell. Biol. |volume=22 |issue= 12 |pages= 4001–10 |year= 2002 |pmid= 12024014 |doi=10.1128/MCB.22.12.4001-4010.2002 | pmc=133842 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Raffetseder U, Frye B, Rauen T, etal |title=Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection. |journal=J. Biol. Chem. |volume=278 |issue= 20 |pages= 18241–8 |year= 2003 |pmid= 12604611 |doi= 10.1074/jbc.M212518200 |doi-access= free }}
- {{cite journal |author1=Xu Q |author2=Leung DY |author3=Kisich KO |title=Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophils. |journal=J. Biol. Chem. |volume=278 |issue= 29 |pages= 27112–8 |year= 2003 |pmid= 12738786 |doi= 10.1074/jbc.M300824200 |doi-access=free }}
- {{cite journal |vauthors=Li J, Hawkins IC, Harvey CD, etal |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437–47 |year= 2003 |pmid= 14559993 |doi=10.1128/MCB.23.21.7437-7447.2003 | pmc=207616 }}
- {{cite journal |vauthors=Kondo S, Yamamoto N, Murakami T, etal |title=Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA. |journal=Genes Cells |volume=9 |issue= 2 |pages= 121–30 |year= 2004 |pmid= 15009090 |doi=10.1111/j.1356-9597.2004.00709.x |s2cid=22248867 |doi-access=free }}
- {{cite journal |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 |bibcode=2004PNAS..10112130B |doi-access=free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Wang Y, Wang J, Gao L, etal |title=Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c.SRp55 complex that either recruits or antagonizes htra2beta1. |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 14230–9 |year= 2005 |pmid= 15695522 |doi= 10.1074/jbc.M413846200 |doi-access= free }}
- {{cite journal |vauthors=Scherer SE, Muzny DM, Buhay CJ, etal |title=The finished DNA sequence of human chromosome 12. |journal=Nature |volume=440 |issue= 7082 |pages= 346–51 |year= 2006 |pmid= 16541075 |doi= 10.1038/nature04569 |bibcode=2006Natur.440..346S |doi-access=free }}
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{{PDB Gallery|geneid=8683}}
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