SGMS1
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Phosphatidylcholine:ceramide cholinephosphotransferase 1 is an enzyme that in humans is encoded by the SGMS1 gene.{{cite journal | vauthors = Vladychenskaya IP, Dergunova LV, Limborska SA | title = In vitro and in silico analysis of the predicted human MOB gene encoding a phylogenetically conserved transmembrane protein | journal = Biomolecular Engineering | volume = 18 | issue = 6 | pages = 263–8 | date = Feb 2002 | pmid = 11841947 | doi = 10.1016/S1389-0344(01)00110-1 }}{{cite journal | vauthors = Yamaoka S, Miyaji M, Kitano T, Umehara H, Okazaki T | title = Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells | journal = The Journal of Biological Chemistry | volume = 279 | issue = 18 | pages = 18688–93 | date = Apr 2004 | pmid = 14976195 | doi = 10.1074/jbc.M401205200 | doi-access = free }}{{cite web | title = Entrez Gene: TMEM23 transmembrane protein 23| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=259230}}
Function
References
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Further reading
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- {{cite journal | vauthors = Albi E, Magni MV | title = Sphingomyelin synthase in rat liver nuclear membrane and chromatin | journal = FEBS Letters | volume = 460 | issue = 2 | pages = 369–72 | date = Oct 1999 | pmid = 10544266 | doi = 10.1016/S0014-5793(99)01378-2 | s2cid = 3025859 | doi-access = }}
- {{cite journal | vauthors = Huitema K, van den Dikkenberg J, Brouwers JF, Holthuis JC | title = Identification of a family of animal sphingomyelin synthases | journal = The EMBO Journal | volume = 23 | issue = 1 | pages = 33–44 | date = Jan 2004 | pmid = 14685263 | pmc = 1271672 | doi = 10.1038/sj.emboj.7600034 }}
- {{cite journal | vauthors = Vladychenskaya IP, Dergunova LV, Dmitrieva VG, Limborska SA | title = Human gene MOB: structure specification and aspects of transcriptional activity | journal = Gene | volume = 338 | issue = 2 | pages = 257–65 | date = Sep 2004 | pmid = 15315829 | doi = 10.1016/j.gene.2004.06.003 }}
- {{cite journal | vauthors = Dong J, Liu J, Lou B, Li Z, Ye X, Wu M, Jiang XC | title = Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice | journal = Journal of Lipid Research | volume = 47 | issue = 6 | pages = 1307–14 | date = Jun 2006 | pmid = 16508036 | doi = 10.1194/jlr.M600040-JLR200 |doi-access=free }}
- {{cite journal | vauthors = Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY | title = A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration | journal = Cell | volume = 125 | issue = 4 | pages = 801–14 | date = May 2006 | pmid = 16713569 | doi = 10.1016/j.cell.2006.03.032 | s2cid = 13709685 | doi-access = free }}
- {{cite journal | vauthors = Tafesse FG, Huitema K, Hermansson M, van der Poel S, van den Dikkenberg J, Uphoff A, Somerharju P, Holthuis JC | title = Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells | journal = The Journal of Biological Chemistry | volume = 282 | issue = 24 | pages = 17537–47 | date = Jun 2007 | pmid = 17449912 | doi = 10.1074/jbc.M702423200 | doi-access = free }}
- {{cite journal | vauthors = Separovic D, Hanada K, Maitah MY, Nagy B, Hang I, Tainsky MA, Kraniak JM, Bielawski J | title = Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage | journal = Biochemical and Biophysical Research Communications | volume = 358 | issue = 1 | pages = 196–202 | date = Jun 2007 | pmid = 17467659 | pmc = 2701614 | doi = 10.1016/j.bbrc.2007.04.095 }}
- {{cite journal | vauthors = Li Z, Hailemariam TK, Zhou H, Li Y, Duckworth DC, Peake DA, Zhang Y, Kuo MS, Cao G, Jiang XC | title = Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization | journal = Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | volume = 1771 | issue = 9 | pages = 1186–94 | date = Sep 2007 | pmid = 17616479 | pmc = 2712822 | doi = 10.1016/j.bbalip.2007.05.007 }}
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{{PDB Gallery|geneid=259230}}
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