Login
Login

SIGLEC5

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Sialic acid-binding Ig-like lectin 5 is a protein that in humans is encoded by the SIGLEC5 gene.{{cite journal | author = Kim HS | title = Assignment of the human OB binding protein-2 gene (CD33L2) to chromosome 19q13.3 by radiation hybrid mapping | journal = Cytogenet Cell Genet | volume = 84 | issue = 1–2 | pages = 96 |date=Jun 1999 | pmid = 10343116 | doi =10.1159/000015227 | s2cid = 10581090 }}{{cite web | title = Entrez Gene: SIGLEC5 sialic acid binding Ig-like lectin 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8778}} SIGLEC5 has also been designated CD170 (cluster of differentiation 170).

References

{{reflist}}

Further reading

{{refbegin | 2}}

  • {{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
  • {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
  • {{cite journal |vauthors=Cornish AL, Freeman S, Forbes G, etal |title=Characterization of siglec-5, a novel glycoprotein expressed on myeloid cells related to CD33 |journal=Blood |volume=92 |issue= 6 |pages= 2123–32 |year= 1998 |pmid= 9731071 |doi= 10.1182/blood.V92.6.2123}}
  • {{cite journal |vauthors=Patel N, Brinkman-Van der Linden EC, Altmann SW, etal |title=OB-BP1/Siglec-6. A leptin- and sialic acid-binding protein of the immunoglobulin superfamily |journal=J. Biol. Chem. |volume=274 |issue= 32 |pages= 22729–38 |year= 1999 |pmid= 10428856 |doi=10.1074/jbc.274.32.22729 |doi-access=free }}
  • {{cite journal | vauthors=Yousef GM, Ordon MH, Foussias G, Diamandis EP |title=Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes |journal=Gene |volume=286 |issue= 2 |pages= 259–70 |year= 2002 |pmid= 11943481 |doi=10.1016/S0378-1119(02)00432-8 }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Erickson-Miller CL, Freeman SD, Hopson CB, etal |title=Characterization of Siglec-5 (CD170) expression and functional activity of anti-Siglec-5 antibodies on human phagocytes |journal=Exp. Hematol. |volume=31 |issue= 5 |pages= 382–8 |year= 2003 |pmid= 12763136 |doi=10.1016/S0301-472X(03)00046-8 |doi-access=free }}
  • {{cite journal |vauthors=Grimwood J, Gordon LA, Olsen A, etal |title=The DNA sequence and biology of human chromosome 19 |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 |bibcode=2004Natur.428..529G |doi-access= free }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
  • {{cite journal |vauthors=Avril T, Freeman SD, Attrill H, etal |title=Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation |journal=J. Biol. Chem. |volume=280 |issue= 20 |pages= 19843–51 |year= 2005 |pmid= 15769739 |doi= 10.1074/jbc.M502041200 |s2cid=44764751 |url=http://www.jbc.org/content/280/20/19843.full.pdf |doi-access=free }}
  • {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 }}
  • {{cite journal |vauthors=Rapoport EM, Pazynina GV, Sablina MA, etal |title=Probing sialic acid binding Ig-like lectins (siglecs) with sulfated oligosaccharides |journal=Biochemistry Mosc. |volume=71 |issue= 5 |pages= 496–504 |year= 2006 |pmid= 16732727 |doi=10.1134/S0006297906050051 |s2cid=11537303 }}
  • {{cite journal | vauthors=Biedermann B, Gil D, Bowen DT, Crocker PR |title=Analysis of the CD33-related siglec family reveals that Siglec-9 is an endocytic receptor expressed on subsets of acute myeloid leukemia cells and absent from normal hematopoietic progenitors |journal=Leuk. Res. |volume=31 |issue= 2 |pages= 211–20 |year= 2007 |pmid= 16828866 |doi= 10.1016/j.leukres.2006.05.026 }}
  • {{cite journal |vauthors=Angata T, Hayakawa T, Yamanaka M, etal |title=Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates |journal=FASEB J. |volume=20 |issue= 12 |pages= 1964–73 |year= 2006 |pmid= 17012248 |doi= 10.1096/fj.06-5800com |doi-access=free |s2cid=13740587 }}
  • {{cite journal | vauthors=Zhuravleva MA, Trandem K, Sun PD |journal=J. Mol. Biol. |volume=375 |issue= 2 |pages= 437–47 |year= 2007 |pmid= 18022638 |doi= 10.1016/j.jmb.2007.10.009 | pmc=2245879 |title=Structural Implications of Siglec-5-Mediated Sialoglycan Recognition }}

{{refend}}

External links

  • [https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/O15389 PDBe-KB] provides an overview of all the structure information available in the PDB for Human Sialic acid-binding Ig-like lectin 5 (SIGLEC5)

{{Clusters of differentiation}}

Category:Clusters of differentiation

Category:SIGLEC

{{membrane-protein-stub}}