SIGLEC7

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• {{cite journal | vauthors=Reif K, Buday L, Downward J, Cantrell DA |title=SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases. |journal=J. Biol. Chem. |volume=269 |issue= 19 |pages= 14081–7 |year= 1994 |doi=10.1016/S0021-9258(17)36757-1 |pmid= 8188688 |doi-access=free }}
• {{cite journal |vauthors=Falco M, Biassoni R, Bottino C, etal |title=Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells. |journal=J. Exp. Med. |volume=190 |issue= 6 |pages= 793–802 |year= 1999 |pmid= 10499918 |doi=10.1084/jem.190.6.793 | pmc=2195632 }}
• {{cite journal |vauthors=Ye X, Mehlen P, Rabizadeh S, etal |title=TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction. |journal=J. Biol. Chem. |volume=274 |issue= 42 |pages= 30202–8 |year= 1999 |pmid= 10514511 |doi=10.1074/jbc.274.42.30202 |doi-access=free }}
• {{cite journal |vauthors=Vitale C, Romagnani C, Falco M, etal |title=Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 26 |pages= 15091–6 |year= 2000 |pmid= 10611343 |doi=10.1073/pnas.96.26.15091 | pmc=24778 |doi-access=free }}
• {{cite journal | vauthors=Angata T, Varki A |title=Siglec-7: a sialic acid-binding lectin of the immunoglobulin superfamily. |journal=Glycobiology |volume=10 |issue= 4 |pages= 431–8 |year= 2000 |pmid= 10764831 |doi=10.1093/glycob/10.4.431 |doi-access=free }}
• {{cite journal |vauthors=Ito A, Handa K, Withers DA, etal |title=Binding specificity of siglec7 to disialogangliosides of renal cell carcinoma: possible role of disialogangliosides in tumor progression. |journal=FEBS Lett. |volume=498 |issue= 1 |pages= 116–20 |year= 2001 |pmid= 11389909 |doi=10.1016/S0014-5793(01)02476-0 |s2cid=6755832 |doi-access=free }}
• {{cite book |vauthors=Mingari MC, Vitale C, Romagnani C, etal |title=Progress in Basic and Clinical Immunology |chapter=Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 surface receptors |volume=495 |pages= 55–61 |pmid= 11774609 |doi= 10.1007/978-1-4615-0685-0_8|series=Advances in Experimental Medicine and Biology |date=2001 |isbn=978-1-4613-5194-8 }}
• {{cite journal | vauthors=Yousef GM, Ordon MH, Foussias G, Diamandis EP |title=Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes. |journal=Gene |volume=286 |issue= 2 |pages= 259–70 |year= 2002 |pmid= 11943481 |doi=10.1016/S0378-1119(02)00432-8 }}
• {{cite journal | vauthors=Alphey MS, Attrill H, Crocker PR, van Aalten DM |title=High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family. |journal=J. Biol. Chem. |volume=278 |issue= 5 |pages= 3372–7 |year= 2003 |pmid= 12438315 |doi= 10.1074/jbc.M210602200 |doi-access= free }}
• {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
• {{cite journal |vauthors=Nicoll G, Avril T, Lock K, etal |title=Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms. |journal=Eur. J. Immunol. |volume=33 |issue= 6 |pages= 1642–8 |year= 2003 |pmid= 12778482 |doi= 10.1002/eji.200323693 |s2cid=7541832 |doi-access=free }}
• {{cite journal |vauthors=Dimasi N, Moretta A, Moretta L, etal |title=Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1. |journal=Acta Crystallogr. D |volume=60 |issue= Pt 2 |pages= 401–3 |year= 2004 |pmid= 14747738 |doi= 10.1107/S0907444903028439 }}
• {{cite journal | vauthors=Ikehara Y, Ikehara SK, Paulson JC |title=Negative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9. |journal=J. Biol. Chem. |volume=279 |issue= 41 |pages= 43117–25 |year= 2004 |pmid= 15292262 |doi= 10.1074/jbc.M403538200 |doi-access= free }}
• {{cite journal |vauthors=Avril T, Floyd H, Lopez F, etal |title=The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by Siglecs-7 and -9, CD33-related Siglecs expressed on human monocytes and NK cells. |journal=J. Immunol. |volume=173 |issue= 11 |pages= 6841–9 |year= 2005 |pmid= 15557178 |doi= 10.4049/jimmunol.173.11.6841|doi-access=free }}
• {{cite journal | vauthors=Yamaji T, Mitsuki M, Teranishi T, Hashimoto Y |title=Characterization of inhibitory signaling motifs of the natural killer cell receptor Siglec-7: attenuated recruitment of phosphatases by the receptor is attributed to two amino acids in the motifs. |journal=Glycobiology |volume=15 |issue= 7 |pages= 667–76 |year= 2005 |pmid= 15703304 |doi= 10.1093/glycob/cwi048 |doi-access= free }}
• {{cite journal |vauthors=Attrill H, Takazawa H, Witt S, etal |title=The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design. |journal=Biochem. J. |volume=397 |issue= 2 |pages= 271–8 |year= 2006 |pmid= 16623661 |doi= 10.1042/BJ20060103 | pmc=1513286 }}
• {{cite journal |vauthors=Rapoport EM, Pazynina GV, Sablina MA, etal |title=Probing sialic acid binding Ig-like lectins (siglecs) with sulfated oligosaccharides. |journal=Biochemistry Mosc. |volume=71 |issue= 5 |pages= 496–504 |year= 2006 |pmid= 16732727 |doi=10.1134/S0006297906050051 |s2cid=11537303 }}
• {{cite journal | vauthors=Biedermann B, Gil D, Bowen DT, Crocker PR |title=Analysis of the CD33-related siglec family reveals that Siglec-9 is an endocytic receptor expressed on subsets of acute myeloid leukemia cells and absent from normal hematopoietic progenitors. |journal=Leuk. Res. |volume=31 |issue= 2 |pages= 211–20 |year= 2007 |pmid= 16828866 |doi= 10.1016/j.leukres.2006.05.026 }}

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{{PDB Gallery|geneid=27036}}

• {{MeshName|SIGLEC7+protein,+human}}

{{NLM content}}

{{Clusters of differentiation}}

Category:Clusters of differentiation

Category:SIGLEC

{{membrane-protein-stub}}