SIGLEC9

{{Short description|Protein-coding gene in the species Homo sapiens}}

Sialic acid-binding Ig-like lectin 9 is a protein that in humans is encoded by the SIGLEC9 gene.{{cite journal | vauthors = Foussias G, Yousef GM, Diamandis EP | title = Identification and molecular characterization of a novel member of the siglec family (SIGLEC9) | journal = Genomics | volume = 67 | issue = 2 | pages = 171–8 |date=Aug 2000 | pmid = 10903842 | doi = 10.1006/geno.2000.6208 }}{{cite web | title = Entrez Gene: SIGLEC9 sialic acid binding Ig-like lectin 9| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27180}}

References

{{cite journal | vauthors=Yousef GM, Luo LY, Diamandis EP |title=Identification of novel human kallikrein-like genes on chromosome 19q13.3-q13.4 |journal=Anticancer Res. |volume=19 |issue= 4B |pages= 2843–52 |year= 2000 |pmid= 10652563 }}
{{cite journal | vauthors=Angata T, Varki A |title=Cloning, characterization, and phylogenetic analysis of siglec-9, a new member of the CD33-related group of siglecs. Evidence for co-evolution with sialic acid synthesis pathways |journal=J. Biol. Chem. |volume=275 |issue= 29 |pages= 22127–35 |year= 2000 |pmid= 10801860 |doi= 10.1074/jbc.M002775200 |doi-access= free }}
{{cite journal | vauthors=Zhang JQ, Nicoll G, Jones C, Crocker PR |title=Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes |journal=J. Biol. Chem. |volume=275 |issue= 29 |pages= 22121–6 |year= 2000 |pmid= 10801862 |doi= 10.1074/jbc.M002788200 |doi-access= free }}
{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
{{cite journal |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
{{cite journal | vauthors=Sonnenburg JL, Altheide TK, Varki A |title=A uniquely human consequence of domain-specific functional adaptation in a sialic acid-binding receptor |journal=Glycobiology |volume=14 |issue= 4 |pages= 339–46 |year= 2004 |pmid= 14693915 |doi= 10.1093/glycob/cwh039 |doi-access= free }}
{{cite journal |vauthors=Grimwood J, Gordon LA, Olsen A, etal |title=The DNA sequence and biology of human chromosome 19 |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 |bibcode=2004Natur.428..529G |doi-access= free }}
{{cite journal | vauthors=Ikehara Y, Ikehara SK, Paulson JC |title=Negative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9 |journal=J. Biol. Chem. |volume=279 |issue= 41 |pages= 43117–25 |year= 2004 |pmid= 15292262 |doi= 10.1074/jbc.M403538200 |doi-access= free }}
{{cite journal |vauthors=Avril T, Floyd H, Lopez F, etal |title=The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by Siglecs-7 and -9, CD33-related Siglecs expressed on human monocytes and NK cells |journal=J. Immunol. |volume=173 |issue= 11 |pages= 6841–9 |year= 2005 |pmid= 15557178 |doi= 10.4049/jimmunol.173.11.6841|doi-access=free }}
{{cite journal |vauthors=von Gunten S, Yousefi S, Seitz M, etal |title=Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment |journal=Blood |volume=106 |issue= 4 |pages= 1423–31 |year= 2005 |pmid= 15827126 |doi= 10.1182/blood-2004-10-4112 |doi-access= free }}
{{cite journal |vauthors=Rapoport EM, Pazynina GV, Sablina MA, etal |title=Probing sialic acid binding Ig-like lectins (siglecs) with sulfated oligosaccharides |journal=Biochemistry Mosc. |volume=71 |issue= 5 |pages= 496–504 |year= 2006 |pmid= 16732727 |doi=10.1134/S0006297906050051 |s2cid=11537303 }}
{{cite journal | vauthors=Biedermann B, Gil D, Bowen DT, Crocker PR |title=Analysis of the CD33-related siglec family reveals that Siglec-9 is an endocytic receptor expressed on subsets of acute myeloid leukemia cells and absent from normal hematopoietic progenitors |journal=Leuk. Res. |volume=31 |issue= 2 |pages= 211–20 |year= 2007 |pmid= 16828866 |doi= 10.1016/j.leukres.2006.05.026 }}

SIGLEC9

References

Further reading