SLFN14

The protein encoded by this gene plays an important role in platelet formation and function. Defects in this gene are a cause of thrombocytopenia with excessive bleeding. [provided by RefSeq, Jul 2016].

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• {{cite journal |vauthors=Fletcher SJ, Johnson B, Lowe GC, Bem D, Drake S, Lordkipanidzé M, Guiú IS, Dawood B, Rivera J, Simpson MA, Daly ME, Motwani J, Collins PW, Watson SP, Morgan NV |title=SLFN14 mutations underlie thrombocytopenia with excessive bleeding and platelet secretion defects |journal=J. Clin. Invest. |volume=125 |issue=9 |pages=3600–5 |date=September 2015 |pmid=26280575 |pmc=4588283 |doi=10.1172/JCI80347 }}
• {{cite journal |vauthors=Marconi C, Di Buduo CA, Barozzi S, Palombo F, Pardini S, Zaninetti C, Pippucci T, Noris P, Balduini A, Seri M, Pecci A |title=SLFN14-related thrombocytopenia: identification within a large series of patients with inherited thrombocytopenia |journal=Thromb. Haemost. |volume=115 |issue=5 |pages=1076–9 |date=May 2016 |pmid=26769223 |doi=10.1160/TH15-11-0884 }}
• {{cite journal |vauthors=Seong RK, Seo SW, Kim JA, Fletcher SJ, Morgan NV, Kumar M, Choi YK, Shin OS |title=Schlafen 14 (SLFN14) is a novel antiviral factor involved in the control of viral replication |journal=Immunobiology |volume=222 |issue=11 |pages=979–988 |date=November 2017 |pmid=28734654 |pmc=5990420 |doi=10.1016/j.imbio.2017.07.002 }}
• {{cite journal |vauthors=Fletcher SJ, Pisareva VP, Khan AO, Tcherepanov A, Morgan NV, Pisarev AV |title=Role of the novel endoribonuclease SLFN14 and its disease-causing mutations in ribosomal degradation |journal=RNA |volume=24 |issue=7 |pages=939–949 |date=July 2018 |pmid=29678925 |pmc=6004054 |doi=10.1261/rna.066415.118 }}

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