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SNAG1

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene.{{cite journal | vauthors = Seet LF, Hong W | title = The Phox (PX) domain proteins and membrane traffic | journal = Biochim Biophys Acta | volume = 1761 | issue = 8 | pages = 878–96 |date=Sep 2006 | pmid = 16782399 | doi = 10.1016/j.bbalip.2006.04.011 }}{{cite journal | vauthors = Thornhill PB, Cohn JB, Drury G, Stanford WL, Bernstein A, Desbarats J | title = A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells | journal = FEBS Lett | volume = 581 | issue = 23 | pages = 4455–62 |date=Sep 2007 | pmid = 17761170 | doi = 10.1016/j.febslet.2007.08.025 | s2cid = 23223511 | url = http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=100212 | doi-access = free }}{{cite web | title = Entrez Gene: SNAG1 sorting nexin associated golgi protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=112574}}

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.{{cite web | title = Entrez Gene: SNAG1 sorting nexin associated golgi protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=112574}}

References

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Further reading

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  • {{cite journal | vauthors=Worby CA, Dixon JE |title=Sorting out the cellular functions of sorting nexins |journal=Nat. Rev. Mol. Cell Biol. |volume=3 |issue= 12 |pages= 919–31 |year= 2003 |pmid= 12461558 |doi= 10.1038/nrm974 |s2cid=36361630 }}
  • {{cite journal | vauthors=Xu Y, Seet LF, Hanson B, Hong W |title=The Phox homology (PX) domain, a new player in phosphoinositide signalling |journal=Biochem. J. |volume=360 |issue= Pt 3 |pages= 513–30 |year= 2002 |pmid= 11736640 |doi=10.1042/0264-6021:3600513 | pmc=1222253 }}
  • {{cite journal |vauthors=Ozyildirim AM, Wistow GJ, Gao J, etal |title=The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts |journal=Invest. Ophthalmol. Vis. Sci. |volume=46 |issue= 5 |pages= 1572–80 |year= 2005 |pmid= 15851553 |doi= 10.1167/iovs.04-1380 |citeseerx=10.1.1.123.3574 }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
  • {{cite journal | vauthors=Schulze WX, Mann M |title=A novel proteomic screen for peptide-protein interactions |journal=J. Biol. Chem. |volume=279 |issue= 11 |pages= 10756–64 |year= 2004 |pmid= 14679214 |doi= 10.1074/jbc.M309909200 |doi-access= free }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Teasdale RD, Loci D, Houghton F, etal |title=A large family of endosome-localized proteins related to sorting nexin 1 |journal=Biochem. J. |volume=358 |issue= Pt 1 |pages= 7–16 |year= 2001 |pmid= 11485546 |doi=10.1042/0264-6021:3580007 | pmc=1222026 }}

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{{Sorting nexins}}

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