SNI

• Substitution nucleophilic internal, a chemistry reaction mechanism
• Swedish Standard Industrial Classification, a Swedish economic classification system
• Server Name Indication, an extension to the TLS computer networking protocol

• Scripps Networks Interactive, a media company
• Showtime Networks Inc., an American cable network company
• Siemens Nixdorf Informationssysteme, a former computer hardware company
• Société Nationale d'Investissement, a Moroccan conglomerate
• Sports Network Incorporated, a former American media company

• National Information Service (Brazil), or {{Lang|pt-BR|Serviço Nacional de Informações}}, the former name of the Brazilian Intelligence Agency
• Seicho-no-Ie, a Japanese new religion
• Shelter Now International, a Christian foreign aid organization, based in Germany and historically focused on Pakistan and Afghanistan
• Sistema Nacional de Investigadores, a Mexican government agency
• Soviet Naval Infantry
• Swiss Nanoscience Institute

• Standar Nasional Indonesia (Indonesian National Standard), formulated by the National Standardization Agency

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