SOX30
{{Short description|Protein-coding gene in the species Homo sapiens}}{{Infobox gene}}
{{cs1 config|name-list-style=vanc|display-authors=6}}
SRY (sex determining region Y)-box 30 is a protein that in humans is encoded by the SOX30 gene.{{cite web | title = Entrez Gene: SRY (sex determining region Y)-box 30 | url = https://www.ncbi.nlm.nih.gov/gene/11063 | access-date = 2014-05-29 }}
Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
References
{{reflist}}
Further reading
{{refbegin | 2}}
- {{cite journal | vauthors = Koopman P, Schepers G, Brenner S, Venkatesh B | title = Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes | journal = Gene | volume = 328 | pages = 177–186 | date = March 2004 | pmid = 15019997 | doi = 10.1016/j.gene.2003.12.008 }}
- {{cite journal | vauthors = Osaki E, Nishina Y, Inazawa J, Copeland NG, Gilbert DJ, Jenkins NA, Ohsugi M, Tezuka T, Yoshida M, Semba K | title = Identification of a novel Sry-related gene and its germ cell-specific expression | journal = Nucleic Acids Research | volume = 27 | issue = 12 | pages = 2503–2510 | date = June 1999 | pmid = 10359848 | pmc = 148454 | doi = 10.1093/nar/27.12.2503 }}
- {{cite journal | vauthors = Fan BJ, Wang DY, Tham CC, Lam DS, Pang CP | title = Gene expression profiles of human trabecular meshwork cells induced by triamcinolone and dexamethasone | journal = Investigative Ophthalmology & Visual Science | volume = 49 | issue = 5 | pages = 1886–1897 | date = May 2008 | pmid = 18436822 | doi = 10.1167/iovs.07-0414 | doi-access = }}
- {{cite journal | vauthors = Bullejos M, Díaz de la Guardia R, Barragán MJ, Sánchez A | title = HMG-box sequences from microbats homologous to the human SOX30 HMG-box | journal = Genetica | volume = 110 | issue = 2 | pages = 157–162 | year = 2000 | pmid = 11678506 | doi = 10.1023/A:1017914005677 | s2cid = 16100625 }}
{{refend}}
{{NLM content}}
{{gene-5-stub}}