SPG23

{{Short description|Genetic element in the species Homo sapiens}}

{{Infobox_gene}}

Spastic paraplegia 23 (SPG autosomal recessive){{cite web|url=https://www.ncbi.nlm.nih.gov/gene/353293|title=Entrez Gene: Spastic paraplegia 23 (autosomal recessive)}} is a 25cM gene locus at 1q24-q32.{{Cite web|url=https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:21340|title=SPG23 Symbol Report {{!}} HUGO Gene Nomenclature Committee|website=www.genenames.org|access-date=2017-09-29|archive-date=2017-09-29|archive-url=https://web.archive.org/web/20170929183319/https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:21340|url-status=dead}} A genome-wide linkage screen has associated this locus with a type of hereditary spastic paraplegia (HSP).{{cite journal | vauthors = Blumen SC, Bevan S, Abu-Mouch S, Negus D, Kahana M, Inzelberg R, Mazarib A, Mahamid A, Carasso RL, Slor H, Withers D, Nisipeanu P, Navon R, Reid E | title = A locus for complicated hereditary spastic paraplegia maps to chromosome 1q24-q32 | journal = Annals of Neurology | volume = 54 | issue = 6 | pages = 796–803 | date = December 2003 | pmid = 14681889 | doi = 10.1002/ana.10768 | s2cid = 12631177 }}