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SPINK2

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Serine protease inhibitor Kazal-type 2 also known as acrosin-trypsin inhibitor is a protein that in humans is encoded by the SPINK2 gene.{{cite journal | vauthors = Moritz A, Grzeschik KH, Wingender E, Fink E | title = Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II) | journal = Gene | volume = 123 | issue = 2 | pages = 277–81 |date=Mar 1993 | pmid = 8428671 | doi =10.1016/0378-1119(93)90138-S | url = http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-9767-3 }}{{cite web | title = Entrez Gene: SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6691}}

See also

References

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{{cite journal |pmid=21705336 | doi=10.1074/jbc.M111.244905 | volume=286 | issue=33 | title=Impaired spermatogenesis and fertility in mice carrying a mutation in the Spink2 gene expressed predominantly in testes | pmc=3190718 | year=2011 | journal=J. Biol. Chem. | pages=29108–17 | vauthors=Lee B, Park I, Jin S, Choi H, Kwon JT, Kim J, Jeong J, Cho BN, Eddy EM, Cho C| doi-access=free }}

Further reading

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  • {{cite journal |vauthors=Wapenaar MC, Monsuur AJ, Poell J, etal |title=The SPINK gene family and celiac disease susceptibility. |journal=Immunogenetics |volume=59 |issue= 5 |pages= 349–57 |year= 2007 |pmid= 17333166 |doi= 10.1007/s00251-007-0199-5 | pmc=1914236 }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
  • {{cite journal |vauthors=Rockett JC, Patrizio P, Schmid JE, etal |title=Gene expression patterns associated with infertility in humans and rodent models. |journal=Mutat. Res. |volume=549 |issue= 1–2 |pages= 225–40 |year= 2004 |pmid= 15120973 |doi= 10.1016/j.mrfmmm.2003.11.017 }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | vauthors=Fink E, Hehlein-Fink C, Eulitz M |title=Amino acid sequence elucidation of human acrosin-trypsin inhibitor (HUSI-II) reveals that Kazal-type proteinase inhibitors are structurally related to beta-subunits of glycoprotein hormones. |journal=FEBS Lett. |volume=270 |issue= 1–2 |pages= 222–4 |year= 1990 |pmid= 2226783 |doi=10.1016/0014-5793(90)81273-Q |s2cid=1068212 |url=https://epub.ub.uni-muenchen.de/9760/1/Fink_Edwin_9760.pdf }}
  • {{cite journal |vauthors=Collins J, Taube W, Fink E, etal |title=Variants of human seminal acrosin inhibitor (HUSI-II) which inhibit human leukocyte elastase. |journal=Biomed. Biochim. Acta |volume=50 |issue= 4–6 |pages= 683–5 |year= 1992 |pmid= 1801743 }}
  • {{cite journal | vauthors=Möritz A, Lilja H, Fink E |title=Molecular cloning and sequence analysis of the cDNA encoding the human acrosin-trypsin inhibitor (HUSI-II). |journal=FEBS Lett. |volume=278 |issue= 1 |pages= 127–30 |year= 1991 |pmid= 1704312 |doi=10.1016/0014-5793(91)80099-O |s2cid=34332531 |url=http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-9763-1 |doi-access=free }}
  • {{cite journal | vauthors=Dietl T, Kruck J, Schill WB, Fritz H |title=Localization of seminal plasma proteinase inhibitors in human spermatozoa as revealed by the indirect immunofluorescence technique. |journal=Hoppe-Seyler's Z. Physiol. Chem. |volume=357 |issue= 10 |pages= 1333–7 |year= 1977 |pmid= 791787 |doi= 10.1515/bchm2.1976.357.2.1333}}

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