SPK

SPK may refer to:

SPK (band), Australia
SPK, Soviet cosmonaut maneuvering unit
Simultaneous pancreas-kidney transplant, a type of pancreas transplantation
Socialist Patients' Collective ({{Langx|de|Sozialistisches Patientenkollektiv|links=no}})
Postal code for Spinola Park, St. Julian's, Malta
Stiftung Preußischer Kulturbesitz, the Prussian Cultural Heritage Foundation
Strategic Plan Campine ({{Langx|nl|Strategisch Plan Kempen|links=no}})
Sutton Parkway railway station's station code