SPNS2
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox gene}}
Spinster homolog 2 (Drosophila) is a protein that in humans is encoded by the SPNS2 gene.{{cite web | title = Spinster homolog 2 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/gene/124976| access-date = 2011-12-04}}
Model organisms
The orthologous protein in zebrafish has been shown to transport sphingosine-1-phosphate (S1P) out of cells during vascular development, and human SPNS2 can transport S1P analogues, including the immunomodulating drug FTY720-P.{{cite journal | vauthors = Kawahara A, Nishi T, Hisano Y, Fukui H, Yamaguchi A, Mochizuki N | title = The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors | journal = Science | volume = 323 | issue = 5913 | pages = 524–7 | date = January 2009 | pmid = 19074308 | doi = 10.1126/science.1167449 | bibcode = 2009Sci...323..524K | s2cid = 44826764 | doi-access = free }}{{cite journal | vauthors = Hisano Y, Kobayashi N, Kawahara A, Yamaguchi A, Nishi T | title = The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720 | journal = The Journal of Biological Chemistry | volume = 286 | issue = 3 | pages = 1758–66 | date = January 2011 | pmid = 21084291 | pmc = 3023470 | doi = 10.1074/jbc.M110.171116 | doi-access = free }}