SRPX
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Sushi repeat-containing protein SRPX is a protein that in humans is encoded by the SRPX gene.{{cite journal | vauthors = Meindl A, Carvalho MR, Herrmann K, Lorenz B, Achatz H, Lorenz B, Apfelstedt-Sylla E, Wittwer B, Ross M, Meitinger T | title = A gene (SRPX) encoding a sushi-repeat-containing protein is deleted in patients with X-linked retinitis pigmentosa | journal = Hum Mol Genet | volume = 4 | issue = 12 | pages = 2339–46 |date=Jul 1996 | pmid = 8634708 | doi =10.1093/hmg/4.12.2339 }}{{cite journal |vauthors=Dry KL, Aldred MA, Edgar AJ, Brown J, Manson FD, Ho MF, Prosser J, Hardwick LJ, Lennon AA, Thomson K, etal | title = Identification of a novel gene, ETX1 from Xp21.1, a candidate gene for X-linked retintis pigmentosa (RP3) | journal = Hum Mol Genet | volume = 4 | issue = 12 | pages = 2347–53 |date=Jul 1996 | pmid = 8634709 | doi =10.1093/hmg/4.12.2347 }}{{cite web | title = Entrez Gene: SRPX sushi-repeat-containing protein, X-linked| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8406}} Bioinformatics analysis suggests the SRPX protein is a peroxiredoxin.{{cite journal |vauthors=Pawłowski K, Muszewska A, Lenart A, etal |title=A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins |journal=BMC Genomics |volume=11 |pages= 590 |year= 2010 |pmid=20964819|doi= 10.1186/1471-2164-11-590 |pmc=3091736 |doi-access=free }}
References
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Further reading
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- {{cite journal |vauthors=Nangaku M, Shankland SJ, Kurokawa K, etal |title=Cloning of a new human gene with short consensus repeats using the EST database |journal=Immunogenetics |volume=46 |issue= 2 |pages= 99–103 |year= 1997 |pmid= 9162095 |doi=10.1007/s002510050247 |s2cid=23621385 }}
- {{cite journal |vauthors=Shimakage M, Takami K, Kodama K, etal |title=Expression of drs mRNA in human lung adenocarcinomas |journal=Hum. Pathol. |volume=33 |issue= 6 |pages= 615–9 |year= 2002 |pmid= 12152160 |doi=10.1053/hupa.2002.125373 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Shin BK, Wang H, Yim AM, etal |title=Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7607–16 |year= 2003 |pmid= 12493773 |doi= 10.1074/jbc.M210455200 |doi-access= free }}
- {{cite journal |vauthors=Mukaisho K, Suo M, Shimakage M, etal |title=Down-regulation of drs mRNA in colorectal neoplasms |journal=Jpn. J. Cancer Res. |volume=93 |issue= 8 |pages= 888–93 |year= 2003 |pmid= 12716466 |pmc=5927109 |doi= 10.1111/j.1349-7006.2002.tb01334.x}}
- {{cite journal |vauthors=Kim CJ, Shimakage M, Kushima R, etal |title=Down-regulation of drs mRNA in human prostate carcinomas |journal=Hum. Pathol. |volume=34 |issue= 7 |pages= 654–7 |year= 2003 |pmid= 12874760 |doi=10.1016/S0046-8177(03)00240-5 }}
- {{cite journal |vauthors=Tambe Y, Isono T, Haraguchi S, etal |title=A novel apoptotic pathway induced by the drs tumor suppressor gene |journal=Oncogene |volume=23 |issue= 17 |pages= 2977–87 |year= 2004 |pmid= 15021917 |doi= 10.1038/sj.onc.1207419 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Ross MT, Grafham DV, Coffey AJ, etal |title=The DNA sequence of the human X chromosome |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 | pmc=2665286 |bibcode=2005Natur.434..325R }}
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