ST3GAL4
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
{{chem name|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase}} is an enzyme that in humans is encoded by the ST3GAL4 gene.{{cite journal | vauthors = Kitagawa H, Mattei MG, Paulson JC | title = Genomic organization and chromosomal mapping of the Gal beta 1,3GalNAc/Gal beta 1,4GlcNAc alpha 2,3-sialyltransferase | journal = J Biol Chem | volume = 271 | issue = 2 | pages = 931–8 |date=Feb 1996 | pmid = 8557707 | doi =10.1074/jbc.271.2.931 | doi-access = free }}{{cite journal | vauthors = Kitagawa H, Paulson JC | title = Cloning of a novel alpha 2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups | journal = J Biol Chem | volume = 269 | issue = 2 | pages = 1394–401 |date=Feb 1994 | doi = 10.1016/S0021-9258(17)42271-X | pmid = 8288606 | doi-access = free }}{{cite web | title = Entrez Gene: ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6484}}
References
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Further reading
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- {{cite journal |vauthors=Kalyanaraman VS, Rodriguez V, Veronese F, etal |title=Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1 |journal=AIDS Res. Hum. Retroviruses |volume=6 |issue= 3 |pages= 371–80 |year= 1990 |pmid= 2187500 |doi=10.1089/aid.1990.6.371 |url=https://zenodo.org/record/1235229 }}
- {{cite journal | vauthors=Pal R, Hoke GM, Sarngadharan MG |title=Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 9 |pages= 3384–8 |year= 1989 |pmid= 2541446 |doi=10.1073/pnas.86.9.3384 | pmc=287137 |bibcode=1989PNAS...86.3384P |doi-access=free }}
- {{cite journal | vauthors=Dewar RL, Vasudevachari MB, Natarajan V, Salzman NP |title=Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport |journal=J. Virol. |volume=63 |issue= 6 |pages= 2452–6 |year= 1989 |pmid= 2542563 |doi= 10.1128/jvi.63.6.2452-2456.1989| pmc=250699 }}
- {{cite journal |vauthors=Kozarsky K, Penman M, Basiripour L, etal |title=Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein |journal=J. Acquir. Immune Defic. Syndr. |volume=2 |issue= 2 |pages= 163–9 |year= 1989 |pmid= 2649653 }}
- {{cite journal | vauthors=Robinson WE, Montefiori DC, Mitchell WM |title=Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis |journal=AIDS Res. Hum. Retroviruses |volume=3 |issue= 3 |pages= 265–82 |year= 1988 |pmid= 2829950 |doi=10.1089/aid.1987.3.265 }}
- {{cite journal | author=Munro S |title=An investigation of the role of transmembrane domains in Golgi protein retention |journal=EMBO J. |volume=14 |issue= 19 |pages= 4695–704 |year= 1995 |pmid= 7588599 |doi= 10.1002/j.1460-2075.1995.tb00151.x| pmc=394566 }}
- {{cite journal | vauthors=Chang ML, Eddy RL, Shows TB, Lau JT |title=Three genes that encode human beta-galactoside alpha 2,3-sialyltransferases. Structural analysis and chromosomal mapping studies |journal=Glycobiology |volume=5 |issue= 3 |pages= 319–25 |year= 1995 |pmid= 7655169 |doi=10.1093/glycob/5.3.319 }}
- {{cite journal |vauthors=Sasaki K, Watanabe E, Kawashima K, etal |title=Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection |journal=J. Biol. Chem. |volume=268 |issue= 30 |pages= 22782–7 |year= 1993 |doi=10.1016/S0021-9258(18)41595-5 |pmid= 7901202 |doi-access=free }}
- {{cite journal | vauthors=Basu SS, Basu M, Li Z, Basu S |title=Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line |journal=Biochemistry |volume=35 |issue= 16 |pages= 5166–74 |year= 1996 |pmid= 8611500 |doi= 10.1021/bi960239l }}
- {{cite journal |vauthors=Saito S, Yamashita S, Endoh M, etal |title=Clinical significance of ST3Gal IV expression in human renal cell carcinoma |journal=Oncol. Rep. |volume=9 |issue= 6 |pages= 1251–5 |year= 2003 |pmid= 12375029 |doi= 10.3892/or.9.6.1251}}
- {{cite journal | vauthors=Grahn A, Larson G |title=Identification of nine alternatively spliced alpha2,3-sialyltransferase, ST3Gal IV, transcripts and analysis of their expression by RT-PCR and laser-induced fluorescent capillary electrophoresis (LIF-CE) in twenty-one human tissues |journal=Glycoconj. J. |volume=18 |issue= 10 |pages= 759–67 |year= 2003 |pmid= 12441665 |doi=10.1023/A:1021199300718 |s2cid=11260655 }}
- {{cite journal |vauthors=Moody AM, North SJ, Reinhold B, etal |title=Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7240–6 |year= 2003 |pmid= 12459555 |doi= 10.1074/jbc.M210468200 |doi-access= free }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal | vauthors=Taniguchi A, Hioki M, Matsumoto K |title=Transcriptional regulation of human Galbeta1,3GalNAc/Galbeta1, 4GlcNAc alpha2,3-sialyltransferase (hST3Gal IV) gene in testis and ovary cell lines |journal=Biochem. Biophys. Res. Commun. |volume=301 |issue= 3 |pages= 764–8 |year= 2003 |pmid= 12565846 |doi=10.1016/S0006-291X(03)00041-X }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal | vauthors=Higai K, Miyazaki N, Azuma Y, Matsumoto K |title=Interleukin-1beta induces sialyl Lewis X on hepatocellular carcinoma HuH-7 cells via enhanced expression of ST3Gal IV and FUT VI gene |journal=FEBS Lett. |volume=580 |issue= 26 |pages= 6069–75 |year= 2007 |pmid= 17054948 |doi= 10.1016/j.febslet.2006.09.073 |s2cid=9731951 |doi-access= }}
- {{cite journal |vauthors=Szabo R, Skropeta D, etal |title=Advancement of Sialyltransferase Inhibitors: Therapeutic Challenges and Opportunities. |journal=Med. Res. Rev. |volume=37 |issue=2 |pages= 210–270 |year= 2017 |doi= 10.1002/med.21407 |url=http://ro.uow.edu.au/cgi/viewcontent.cgi?article=5226&context=smhpapers |pmid=27678392|s2cid=26280291 }}
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