San Polo Matese

{{Use dmy dates|date=August 2023}}

{{Infobox Italian comune

| name = San Polo Matese

| official_name = Comune di San Polo Matese

| native_name =

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| image_shield = SanPoloMatese-Stemma.gif

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| coordinates = {{coord|41|28|N|14|30|E|type:city(465)_region:IT|display=inline}}

| coordinates_footnotes =

| region = Molise

| province = Campobasso (CB)

| frazioni =

| mayor_party =

| mayor = Tonino Spina

| area_footnotes =

| area_total_km2 = 17.7

| population_footnotes =All demographics and other statistics: Italian statistical institute Istat.

| population_total = 485

| population_as_of = Dec. 2004

| pop_density_footnotes =

| population_demonym = Sanpolesi

| elevation_footnotes =

| elevation_m = 751

| twin1 =

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| saint = St. Nicholas

| day =6 December

| postal_code = 86020

| area_code = 0874

| website =

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}}

San Polo Matese is a comune (municipality) in the Province of Campobasso in the Italian region Molise, located about {{convert|20|km|mi}} southwest of Campobasso.

San Polo Matese borders the following municipalities: Bojano, Campochiaro, Colle d'Anchise, San Gregorio Matese.