Sangre de Cristo Creek

{{Infobox river

| name = Sangre de Cristo Creek

| image = Sangre de Cristo Creek.JPG

| image_size = 250px

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| image_caption = The creek near Fort Garland, viewed from a bridge on Trinchera Ranch Road North.

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| name_native =

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| source1_location = La Veta Pass

| source1_coordinates= {{coord|37|36|56|N|105|11|35|W}}

|source1_coord_ref = {{cite gnis|id= 192760|name=Sangre de Cristo Creek|accessdate= 2018-04-23}}

| mouth_location = Smith Reservoir

| mouth_coordinates = {{coord|37|23|54|N|105|31|25|W|display=inline,title}}

| progression = Trinchera Creek — Rio Grande

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| mouth_elevation = {{convert|7730|ft|m|abbr=off|sp=us}}

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Sangre de Cristo Creek is a stream in Costilla County, Colorado. It starts atop La Veta Pass in the Sangre de Cristo Mountains. The creek flows alongside Highway 160 as it descends from the top of the pass into the San Luis Valley.

The creek's mouth is at Smith Reservoir, south of Blanca. Before the reservoir was built, the creek had a confluence here with Trinchera Creek, of which it is a tributary.

In 1879 there was a railroad accident on a grade above the creek, killing one person.{{cite news |title=Perils of Mountain Railroading |url=https://www.newspapers.com/image/427078420/ |access-date=16 August 2021 |work=The Garden City Paper (Kansas) |date=25 September 1879 |location=Garden City, Kansas |page=2 |quote=...the train was cut at the little station at Sangre de Cristo Creek, on the west side of the Sangre de Cristo Range, being too heavy for the engine to take up the grade.}}