Sankar Adhya
{{Short description|Microbiologist}}
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{{Use Indian English|date=February 2019}}
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| birth_place = Kolkata, India
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Sankar Adhya (born 4 October 1937) is a molecular biologist and geneticist at the National Cancer Institute (NCI){{cite web | url=https://ccr.cancer.gov/Laboratory-of-Molecular-Biology/sankar-adhya| title=Sankar Adhya Ph.D.|agency=National Cancer Institute|access-date=2016-11-17}} and a member of the National Academy of Sciences.{{cite web | url=http://nrc88.nas.edu/pnas_search/memberDetails.aspx?ctID=66170| title=Sankar Adhya |agency=National Academy of Sciences|access-date=2016-11-17}} He is best known for his work on bacterial transcription and the biology of bacteriophage lambda. He has made important contributions regarding the physical basis of transcriptional regulation in bacteria, the lysis/lysogeny switch in lambda phage, the organization of the bacterial nucleoid, and phage therapy.
Life
Adhya was born in Kolkata, India and studied chemistry at the University of Calcutta as an undergraduate. He later obtained a Ph.D. from the University of Calcutta in biochemistry and a second Ph.D. in genetics from the University of Wisconsin–Madison. Following postdoctoral training at Stanford University, the Bose Institute, and the University of Rochester, he joined the NCI's newly formed Laboratory of Molecular Biology (LMB) in 1971.{{cite web|last1=Adhya|first1=Sankar|author2=Gant, Jason|title=NCI Laboratory of Molecular Biology Oral History Project|url=https://history.nih.gov/archives/downloads/2008%2010%2001%20Sankar%20Adhya%201%20-%20Oral%20History.pdf |date=1 October 2008}}{{cite web|last1=Adhya|first1=Sankar|author2=Gant, Jason|title=NCI Laboratory of Molecular Biology Oral History Project|url=https://history.nih.gov/archives/downloads/2008%2010%2008%20Sankar%20Adhya%202%20-%20Oral%20History.pdf|date=8 October 2008}} He has remained at the NIH since 1971 and is presently Head of the LMB's Developmental Genetics section.
Awards and honors
- Elected to the National Academy of Sciences in 1994.
- Elected to the Indian National Science Academy in 1995.
- Elected to the American Academy of Arts and Sciences in 2009.
- Elected to the Hungarian Academy of Sciences in 2010 as a foreign member.
Selected publications
- {{cite journal|last1=Adhya|first1=S|last2=Gottesman|first2=M|title=Control of transcription termination|journal=Annual Review of Biochemistry|date=1978|volume=47|issue=1|pages=967–996|pmid=354508|doi=10.1146/annurev.bi.47.070178.004535}}
- {{cite journal|last1=Irani|first1=M|last2=Orosz|first2=L|last3=Adhya|first3=S|title=A control element within a structural gene: the gal operon of Escherichia coli|journal=Cell|date=1983|volume=32|issue=3|pages=783–788|pmid=6299576|doi=10.1016/0092-8674(83)90064-8|s2cid=41077642}}
- {{cite journal|last1=Adhya|first1=S|title=Multipartite genetic control elements: communication by DNA loop|journal=Annual Review of Genetics|date=1989|volume=23|issue=1|pages=227–250|pmid=2694932|doi=10.1146/annurev.ge.23.120189.001303}}
- {{cite journal|last1=Merril|first1=C|last2=Biswas|first2=B|last3=Carlton|first3=R|last4=Jensen|first4=N|last5=Creed|first5=G|last6=Zullo|first6=S|last7=Adhya|first7=S|title=Long-circulating bacteriophage as antibacterial agents|journal=Proceedings of the National Academy of Sciences|date=1996|volume=93|issue=8|pages=3188–3192|pmid=8622911|doi=10.1073/pnas.93.8.3188|pmc=39580|bibcode=1996PNAS...93.3188M|doi-access=free}}
- {{cite journal|last1=Merril|first1=C|last2=Scholl|first2=D|last3=Adhya|first3=S|title=The prospect for bacteriophage therapy in Western medicine|journal=Nature Reviews Drug Discovery|date=2003|volume=2|issue=6|pages=489–497|pmid=12776223|doi=10.1038/nrd1111|s2cid=23298353|url=https://zenodo.org/record/1233513}}
- {{cite journal|last1=Oppenheim|first1=A|last2=Kobiler|first2=O|last3=Stavans|first3=J|last4=Court|first4=D|last5=Adhya|first5=S|title=Switches in bacteriophage lambda development|journal=Annual Review of Genetics|date=2005|volume=39|issue=1|pages=409–429|pmid=16285866|doi=10.1146/annurev.genet.39.073003.113656}}
References
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Category:Indian molecular biologists
Category:Genetic epidemiologists
Category:University of Calcutta alumni
Category:Stanford University alumni
Category:University of Wisconsin–Madison College of Agricultural and Life Sciences alumni
Category:Members of the United States National Academy of Sciences
Category:Foreign fellows of the Indian National Science Academy