Santiago de Alcántara

{{Infobox settlement

| settlement_type = municipality

| official_name = Santiago de Alcántara, Spain

| nickname =

| image_flag =

| image_shield = Escudo de Santiago de Alcántara (Cáceres).svg

| image_map =

| image_skyline = Santiago de Alcántara 2.jpg

| map_caption =

| subdivision_type = Country

| subdivision_name = Spain

| subdivision_type1 = Autonomous community

| subdivision_name1 = Extremadura

| subdivision_type2 = Province

| subdivision_name2 = Cáceres

| subdivision_type3 = Municipality

| subdivision_name3 = Santiago de Alcántara

| leader_title =

| leader_name =

| area_magnitude =

| area_total_km2 = 95

| area_land_km2 =

| area_water_km2 =

| elevation_m = 342

| population_note =

| population_as_of = {{Spain metadata Wikidata|population_as_of}}

| population_footnotes = {{Spain metadata Wikidata|population_footnotes}}

| population_total = {{Spain metadata Wikidata|population_total}}

| population_density_km2 = auto

| timezone = CET

| utc_offset = +1

| timezone_DST = CEST

| utc_offset_DST = +2

| latitude =

| longitude =

| website =

| footnotes =

| }}

Santiago de Alcántara is a municipality located in the province of Cáceres, Extremadura, Spain. According to the 2006 census (INE), the municipality has a population of 724 inhabitants.