Selenophos
{{Chembox
| OtherNames = Seleno-VE{{cite book |last1=Mager |first1=Peter P. |title=Multidimensional pharmacochemistry : design of safer drugs |date=1984 |publisher=Academic Press |location=Orlando |isbn=978-0-12-465020-6 |pages=354}}
| PIN = Se-[2-(Diethylamino)ethyl] O-ethyl ethylphosphonoselenoate
| ImageFile = Selenophos.svg
| Section1 = {{Chembox Identifiers
| CASNo = 10161-84-9
| ChemSpiderID = 175244
| PubChem = 202353
| DTXSID = DTXSID00906396
| SMILES = CCN(CC)CC[Se]P(=O)(CC)OCC
| StdInChI = InChI=1S/C10H24NO2PSe/c1-5-11(6-2)9-10-15-14(12,8-4)13-7-3/h5-10H2,1-4H3
| StdInChIKey = QNGZOSUHNXJPIY-UHFFFAOYSA-N
}}
| Section2 = {{Chembox Properties
| C=10|H=24|N=1|O=2|P=1|Se=1
}}
| Section3 = {{Chembox Hazards
| LD50 = 21 μg/kg (mouse, subcutaneous)
}}
}}
Selenophos is an extremely potent organophosphate acetylcholinesterase inhibitor.{{cite journal |last1=Akerfeldt |first1=Stig. |last2=Fagerlind |first2=Lars. |title=Selenophosphorus Compounds as Powerful Cholinesterase Inhibitors |journal=Journal of Medicinal Chemistry |date=January 1967 |volume=10 |issue=1 |pages=115–116 |doi=10.1021/jm00313a032|pmid=6031689 }} It is the selenium analog of the VE nerve agent.
See also
References
{{reflist}}
{{Acetylcholine metabolism and transport modulators}}
{{Chemical agents}}
Category:Acetylcholinesterase inhibitors
Category:Organoselenium compounds
Category:Diethylamino compounds
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