Selenophos

{{Chembox

| Name = Selenophos{{cite journal |last1=Nachmansohn |first1=David |title=Proteins of Excitable Membranes |journal=The Journal of General Physiology |date=1 July 1969 |volume=54 |issue=1 |pages=187–224 |doi=10.1085/jgp.54.1.187 |pmid=19873642 |pmc=2225914}}

| OtherNames = Seleno-VE{{cite book |last1=Mager |first1=Peter P. |title=Multidimensional pharmacochemistry : design of safer drugs |date=1984 |publisher=Academic Press |location=Orlando |isbn=978-0-12-465020-6 |pages=354}}

| PIN = Se-[2-(Diethylamino)ethyl] O-ethyl ethylphosphonoselenoate

| ImageFile = Selenophos.svg

| Section1 = {{Chembox Identifiers

| CASNo = 10161-84-9

| ChemSpiderID = 175244

| PubChem = 202353

| DTXSID = DTXSID00906396

| SMILES = CCN(CC)CC[Se]P(=O)(CC)OCC

| StdInChI = InChI=1S/C10H24NO2PSe/c1-5-11(6-2)9-10-15-14(12,8-4)13-7-3/h5-10H2,1-4H3

| StdInChIKey = QNGZOSUHNXJPIY-UHFFFAOYSA-N

}}

| Section2 = {{Chembox Properties

| C=10|H=24|N=1|O=2|P=1|Se=1

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| Section3 = {{Chembox Hazards

| LD50 = 21 μg/kg (mouse, subcutaneous)

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Selenophos is an extremely potent organophosphate acetylcholinesterase inhibitor.{{cite journal |last1=Akerfeldt |first1=Stig. |last2=Fagerlind |first2=Lars. |title=Selenophosphorus Compounds as Powerful Cholinesterase Inhibitors |journal=Journal of Medicinal Chemistry |date=January 1967 |volume=10 |issue=1 |pages=115–116 |doi=10.1021/jm00313a032|pmid=6031689 }} It is the selenium analog of the VE nerve agent.

See also

References

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{{Acetylcholine metabolism and transport modulators}}

{{Chemical agents}}

Category:Acetylcholinesterase inhibitors

Category:Organoselenium compounds

Category:Ethyl esters

Category:Diethylamino compounds

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