Seneleleni Ndwandwe
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| name = Seneleleni Ndwandwe
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| succession = Ndlovukati of Swaziland
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| predecessor = Zihlathi Ndwandwe/Mkhatjwa{{cite journal|last=Siyinqaba|date=1984|title=The Swazi Monarchy|journal=Africa Insight|volume=14|issue=1|pages=14–16|url=http://reference.sabinet.co.za/webx/access/journal_archive/02562804/241.pdf}}
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| successor = Dzeliwe Shongwe
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Seneleleni Ndwandwe (died 1980), also known as Seneleni Nxumalo, was Ndlovukati (queen mother) of Swaziland during the reign of Sobhuza II. She was full sister and co-wife to her predecessor, Zihlathi Ndwandwe.{{cite news|url=http://www.observer.org.sz/news/72671-happy-mother%E2%80%99s-day-2015.html|title=Happy mother's day 2015|last=Ndwandwe|first=Joy|date=10 May 2015|publisher=Swazi Observer|language=English|accessdate=29 October 2016}}