Sheila Nirenberg

{{short description|American neuroscientist}}

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| name = Sheila Nirenberg

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| caption = Nirenberg in 2013

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| fields = Neuroscience

| workplaces = Cornell University

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| alma_mater = SUNY Albany
Harvard University

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| awards = MacArthur Award, Beckman Young Investigators Award,{{cite news |last1=Guerrero |first1=Russell |title=Talking to the brain in its own language |url=https://new.trinity.edu/news/talking-brain-its-own-language |access-date=1 August 2018 |work=Trinity University |date=March 21, 2014}} TED Talk, NYC BioAccelerate Prize

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| website = {{URL|physiology.med.cornell.edu/faculty/nirenberg/lab/}}

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{{external media | width = 210px | float = right | headerimage= |video1= [https://www.tedmed.com/talks/show?id=7217 ”Sheila Nirenberg, Can we speak the language of the brain?”], TEDMED, 2011 | video2 = [https://www.youtube.com/watch?v=elO4BSHgoy4 “Sheila Nirenberg - Q&A”], TEDMED, 2011 |video3= [https://www.macfound.org/fellows/899/ ”MacArthur Fellows Program, Sheila Nirenberg”], MacArthur Foundation, 2013 }}

Sheila Nirenberg is an American neuroscientist and professor at Weill Cornell Medical College. She works in the field of neural coding, developing new kinds of prosthetic devices that can communicate directly with the brain,{{cite journal |last1=Brumfiel |first1=Geoff |title=Prosthetic retina helps to restore sight in mice |journal=Nature |date=13 August 2012 |doi=10.1038/nature.2012.11164 |s2cid=87951998 |url=https://www.nature.com/news/prosthetic-retina-helps-to-restore-sight-in-mice-1.11164 |access-date=1 August 2018|url-access=subscription }} and new kinds of smart robots.{{cite web |title=Sheila Nirenberg Going from scientist to entrepreneur: things that are useful to know |url=http://www.smc2017.org/?q=Sheila%20Nirenberg |website=IEEE SMC 2017|date= October 6, 2017 |access-date=1 August 2018}} She is a recipient of a MacArthur “genius” award{{cite web|url=http://www.crainsnewyork.com/article/20130926/HEALTH_CARE/130929924/sheila-nirenberg-a-genius-with-vision|title=New Yorker trying cure blindness wins 'genius' prize|first=Barbara|last=Benson|website=crainsnewyork.com}}{{cite news|url=https://www.nytimes.com/2013/09/25/arts/macarthur-genius-award-winners-named.html|title=24 Recipients of MacArthur 'Genius' Awards Named|first=Felicia R.|last=Lee|date=24 September 2013|work=The New York Times}} and has been the subject of, or featured in, several documentaries for her technology for treating blindness.{{cite web|url=http://www.bbc.com/future/story/20141111-the-code-that-may-treat-blindness|title=The code that may treat blindness|first=|last=|website=BBC News|date=12 November 2014}}{{cite web|url=https://www.bloomberg.com/news/articles/2016-04-05/this-bionic-eye-could-cure-blindness|title=This Bionic Eye Could Cure Blindness|first1= Sam|last1= Grobart|first2=Alan|last2= Jeffries|date=5 April 2016|work=Bloomberg}}{{cite web|url=http://storyofsight.com/|title=Sight - The Story of Vision|website=storyofsight.com}}

She is currently the Nanette Laitman Professor in Neurology and Neuroscience and a professor of Computational Neuroscience in the Institute for Computational Biomedicine at the Weill Medical College of Cornell University.{{cite web|url=http://physiology.med.cornell.edu/faculty/nirenberg/lab/|title=Nirenberg Lab Website|website=Cornell University}}{{Cite web|title=Sheila Nirenberg, Ph.D. – Weill Cornell Medicine – Department of Physiology and Biophysics|url=https://physiology.med.cornell.edu/people/sheila-nirenberg-ph-d/|access-date=2020-09-13|language=en-US}} Additionally, she is the founder of two startup companies, Bionic Sight LLC (prosthetic devices){{cite news |last1=Mullin |first1=Emily |title=Companies Plan Tests of "Optogenetic Goggles" to Restore Sight |url=https://www.technologyreview.com/s/603561/companies-plan-tests-of-optogenetic-goggles-to-restore-sight/ |access-date=1 August 2018 |work=MIT Technology Review |date=February 15, 2017}} and Nirenberg Neuroscience LLC (smart robots, AI).{{cite web|url=https://www.nirenbergneuroscience.com/|archive-url=https://web.archive.org/web/20160820085100/http://www.nirenbergneuroscience.com/|url-status=usurped|archive-date=August 20, 2016|title=Homepage|website= Nirenberg Neruoscience, LLC }}

Early life and education

Nirenberg grew up in Westchester, New York, United States. She obtained her bachelor's degree from the State University of New York at Albany and her doctorate from Harvard Medical School.{{Cite journal|last=Talan|first=Jamie|date=2013-11-07|title=BEHIND THE BENCH: What MacArthur Awardee Sheila Nirenberg Is Doing to Help Blind People See|url=https://dx.doi.org/10.1097%2F01.NT.0000438149.22688.f0|journal=Neurology Today|language=en-US|volume=13|issue=21|pages=24|doi=10.1097/01.NT.0000438149.22688.f0|issn=1533-7006|url-access=subscription}}{{Cite web|url=https://www.albany.edu/cas/43695.php|title=UAlbany Psychology Department Alumna Awarded Prestigious MacArthur Fellowship for Pioneering Work in Neuroscience - College of Arts & Sciences - University at Albany-SUNY|website=www.albany.edu|language=en|access-date=2020-03-22}} She worked with Constance Cepko, a neurobiologist who was studying development and degeneration of the vertebrate retina.{{Cite web|title=Sheila Nirenberg - MacArthur Foundation|url=https://www.macfound.org/fellows/899/|access-date=2020-09-13|website=www.macfound.org}} Nirenberg's project focused on developing a new technique to eliminate specific interneuron cell types in order to understand fundamentally how neural circuits work.

Research career

Nirenberg stayed at Harvard University for her postdoctoral work, working in computational neuroscience, then joined the faculty in the Department of Neurobiology at the University of California, Los Angeles (UCLA). She was then recruited to Cornell Medical School (Weill Cornell Medicine), where she is now a full professor {{Cite web|title=Nirenberg, Sheila|url=http://vivo.med.cornell.edu/display/cwid-shn2010|access-date=2020-09-13|website=vivo.med.cornell.edu}} A few years later, she was able to decipher the retina's neural code {{Cite web|last=Salerno|first=Heather|date=2017-03-07|title=Seeing is Believing|url=http://cornellalumnimagazine.com/seeing-is-believing/|access-date=2020-09-13|website=Cornell Alumni Magazine|language=en-US}} This discovery allowed her to develop a new treatment for blindness. The treatment bypasses damaged retinal cells and directly communicates visual information through the optic nerve to the brain. Nirenberg has published her research in journals such as Nature, PNAS, Neuron, and PLoS One. Her company, Bionic Sight, LLC (https://www.bionicsightllc.com/) is currently running a clinical trial to bring the treatment forward to blind patients (ClinicalTrials.gov identifier: NCT04278131).

Awards and honors

  • Bressler Prize, 2022 for Outstanding Accomplishments in Vision Science
  • Barbara McClintock Women Innovator Award, 2022
  • Crain's Notable Women in Tech, 2019{{Cite web|date=2019-05-01|title=Notable Women in Technology - Sheila Nirenberg, Ph.D.|url=https://www.crainsnewyork.com/awards/notable-women-tech-2019-sheila-nirenberg-phd|access-date=2021-09-13|website=Crain's New York Business|language=en}}
  • MacArthur Award, 2013
  • Beckman Young Investigators Award{{Cite web|title=Sheila Nirenberg|url=https://www.worldsciencefestival.com/participants/sheila_nirenberg/|access-date=2020-09-13|website=World Science Festival|language=en-US}}
  • Klingenstein Fellowship, 1998{{Cite web|title=The Esther A. & and Joseph Klingenstein Fund, Inc.|url=https://www.klingfund.org/fellows/fellows98.php|access-date=2020-09-13|website=www.klingfund.org}}
  • Frontiers of Science Award
  • Stein Oppenheimer Award

References

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