Single umbilical artery

SUA does increase the risk of the baby having cardiac, skeletal, intestinal or renal problems.{{Cite web|url=http://www.nhs.uk/chq/pages/2299.aspx?categoryid=54&subcategoryid=128|title=Pregnancy|date=8 December 2020}} Babies with SUA may have a higher likelihood of having other congenital abnormalities, especially of the heart. However, additional testing (high level ultrasound scans) can rule out many of these abnormalities prior to birth and alleviate parental anxiety.{{citation needed|date=February 2021}}

It may be associated with Trisomy 18, also known as Edwards syndrome.{{cite journal |last1=Cereda |first1=Anna |last2=Carey |first2=John C |title=The trisomy 18 syndrome |journal=Orphanet Journal of Rare Diseases |date=2012 |volume=7 |issue=1 |pages=81 |doi=10.1186/1750-1172-7-81 |pmid=23088440 |pmc=3520824 |doi-access=free }} Intrauterine growth restriction has been found to be associated.{{citation needed|date=February 2021}}

It can be detected in the first trimester of pregnancy with the use of 2D ultrasound. The sonographer is able to identify a 2 vessel cord in an image with the bladder and color Doppler, which will show only one artery going around one side of the bladder. In a normal fetus, there would be 2 arteries (one on each side of the bladder).{{cite journal |last1=Martínez-Payo |first1=Cristina |last2=Cabezas |first2=Elena |last3=Nieto |first3=Yolanda |last4=Ruiz de Azúa |first4=Miguel |last5=García-Benasach |first5=Fátima |last6=Iglesias |first6=Enrique |title=Detection of Single Umbilical Artery in the First Trimester Ultrasound: Its Value as a Marker of Fetal Malformation |journal=BioMed Research International |date=2014 |volume=2014 |page=548729 |doi=10.1155/2014/548729|pmid=25101287 |pmc=4101964 |doi-access=free }} Echocardiograms of the fetus may be advised to ensure the heart is functioning properly. Genetic counseling may be useful, too, especially when weighing the pros and cons of more invasive procedures such as chorionic villus sampling and amniocentesis. These invasive procedures are usually performed when there is a suspected chromosomal abnormality or genetic defect and will confirm a diagnosis.{{citation needed|date=January 2021}}

Although the presence of an SUA is a risk factor for additional complications, most fetuses with the condition will not experience other problems, either in utero or after birth. Especially encouraging are cases in which no other soft markers for congenital abnormalities are visible via ultrasound. Given that, the vast majority of expectant mothers do not receive the kind of advanced ultrasound scanning required to confirm SUA in utero.{{citation needed|date=January 2021}}

It is slightly more common in multiple births, in infants with chromosome anomalies, and in girls than in boys.{{cite journal |last1=Lilja |first1=Monica |title=Infants with single umbilical artery studied in a national registry. General epidemiological characteristics |journal=Paediatric and Perinatal Epidemiology |date=January 1991 |volume=5 |issue=1 |pages=27–36 |doi=10.1111/j.1365-3016.1991.tb00681.x |pmid=2000332}}{{cite journal |last1=Heifetz |first1=SA |title=Single umbilical artery. A statistical analysis of 237 autopsy cases and review of the literature. |journal=Perspectives in Pediatric Pathology |year=1984 |volume=8 |issue=4 |pages=345–78 |pmid=6514541}}

• Umbilical cord

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| DiseasesDB = 34592

| ICD10 = {{ICD10|P|02|6}}, {{ICD10|Q|27|0}}

| ICD9 = {{ICD9|747.5}}

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{{Certain conditions originating in the perinatal period}}

{{Medicine}}

{{Congenital vascular defects}}

Category:Congenital vascular defects