Sodalis glossinidius

{{Short description|Species of bacterium}}

{{Italic title}}

{{Taxobox

| name = Sodalis glossinidius

| domain = Bacteria

| phylum = Pseudomonadota

| classis = Gammaproteobacteria

| ordo = Enterobacterales

| familia = Pectobacteriaceae

| genus = Sodalis

| species = S. glossinidius

| species_authority = Dale and Maudlin 1999

}}

Sodalis glossinidius is a species of bacteria, the type and only species of its genus. It is a microaerophilic secondary endosymbiont of the tsetse fly. Strain M1T is the type strain.{{cite journal | vauthors = Dale C, Maudlin I | title = Sodalis gen. nov. and Sodalis glossinidius sp. nov., a microaerophilic secondary endosymbiont of the tsetse fly Glossina morsitans morsitans | journal = International Journal of Systematic Bacteriology | volume = 49 Pt 1 | issue = 1 | pages = 267–75 | date = January 1999 | pmid = 10028272 | doi = 10.1099/00207713-49-1-267 | doi-access = free }} Sodalis glossinidius is the only gammaproteobacterial insect symbiont to be cultured and thus amenable to genetic modification, suggesting that it could be used as part of a control strategy by vectoring antitrypanosome genes. The organism may increase the susceptibility of tsetse flies to trypanosomes.{{cite journal | vauthors = Darby AC, Lagnel J, Matthew CZ, Bourtzis K, Maudlin I, Welburn SC | title = Extrachromosomal DNA of the symbiont Sodalis glossinidius | journal = Journal of Bacteriology | volume = 187 | issue = 14 | pages = 5003–7 | date = July 2005 | pmid = 15995217 | pmc = 1169519 | doi = 10.1128/JB.187.14.5003-5007.2005 }}

Despite gene erosion and pseudogene multiplication in a genome of Sodalis glossinidius,{{cite journal | vauthors = Toh H, Weiss BL, Perkin SA, Yamashita A, Oshima K, Hattori M, Aksoy S | title = Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host | journal = Genome Research | volume = 16 | issue = 2 | pages = 149–56 | date = February 2006 | pmid = 16365377 | pmc = 1361709 | doi = 10.1101/gr.4106106 }} these pseudogenes remain actively transcribed.{{cite journal | vauthors = Goodhead I, Blow F, Brownridge P, Hughes M, Kenny J, Krishna R, McLean L, Pongchaikul P, Beynon R, Darby AC | display-authors = 6 | title = Large-scale and significant expression from pseudogenes in Sodalis glossinidius - a facultative bacterial endosymbiont | journal = Microbial Genomics | volume = 6 | issue = 1 | date = January 2020 | pmid = 31922467 | pmc = 7067036 | doi = 10.1099/mgen.0.000285 | doi-access = free }}