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TBC1D3

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

TBC1 domain family member 3E/3F is a protein that in humans is encoded by the TBC1D3F gene.{{cite journal | vauthors = Hodzic D, Kong C, Wainszelbaum MJ, Charron AJ, Su X, Stahl PD | title = TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12 | journal = Genomics | volume = 88 | issue = 6 | pages = 731–6 |date=Nov 2006 | pmid = 16863688 | doi = 10.1016/j.ygeno.2006.05.009 | doi-access = }}{{cite web | title = Entrez Gene: TBC1D3 TBC1 domain family, member 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84218}}

This gene encodes a protein that is similar to TBC1 domain family, member 3. This protein contains a TBC (Tre-2, Bub2p, and Cdc16p) domain, which is found in proteins involved in Rab GTPase signaling and vesicle trafficking. There are two copies of this gene located within a cluster of chemokine genes on chromosome 17q; this record represents the more centromeric copy.{{cite web | title = Entrez Gene: TBC1D3 TBC1 domain family, member 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84218}}

References

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Further reading

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  • {{cite journal | vauthors=Onno M, Nakamura T, Hillova J, Hill M |title=Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes. |journal=Gene |volume=131 |issue= 2 |pages= 209–15 |year= 1993 |pmid= 8406013 |doi=10.1016/0378-1119(93)90295-E }}
  • {{cite journal |vauthors=Onno M, Nakamura T, Mariage-Samson R, etal |title=Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes. |journal=DNA Cell Biol. |volume=12 |issue= 2 |pages= 107–18 |year= 1993 |pmid= 8471161 |doi=10.1089/dna.1993.12.107 }}
  • {{cite journal | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000 | pmc=310948 }}
  • {{cite journal |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R | pmc=311072 }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | vauthors=Paulding CA, Ruvolo M, Haber DA |title=The Tre2 (USP6) oncogene is a hominoid-specific gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 5 |pages= 2507–11 |year= 2003 |pmid= 12604796 |doi= 10.1073/pnas.0437015100 | pmc=151371 |bibcode=2003PNAS..100.2507P |doi-access=free }}
  • {{cite journal | vauthors=Masuda-Robens JM, Kutney SN, Qi H, Chou MM |title=The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling. |journal=Mol. Cell. Biol. |volume=23 |issue= 6 |pages= 2151–61 |year= 2003 |pmid= 12612085 |doi=10.1128/MCB.23.6.2151-2161.2003 | pmc=149457 }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
  • {{cite journal |vauthors=Wiemann S, Arlt D, Huber W, etal |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 | pmc=528930 }}
  • {{cite journal |vauthors=Mehrle A, Rosenfelder H, Schupp I, etal |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 | pmc=1347501 }}

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