TGF

• Tubuloglomerular feedback, a reflex of the nephrons in the kidney
• Transforming growth factor, either of two classes of polypeptide growth factors (TGF-α and TGF-β)

• Terrestrial gamma-ray flash, a burst of gamma rays produced in the Earth's atmosphere, generally associated with lightning
• Tidal Generating Force, an effect of gravity responsible for creating tides
• Trivial Graph Format, a text-based file format for describing graphs

• The Games Factory, video game development software created by Clickteam
• The Gracious Few, an American rock group from York, Pennsylvania
• TGFbro, British YouTube duo

• Chali language, by ISO 639 code

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