TL-301

{{Chembox

| Name = TL-301

| ImageFile = TL-301.svg

| Section1 = {{Chembox Identifiers

| CASNo = 619-34-1

| PubChem = 32369

| ChemSpiderID = 30001

| StdInChI=1S/C7H15Cl2N/c1-7(2)10(5-3-8)6-4-9/h7H,3-6H2,1-2H3

| StdInChIKey = WAEDMQMDOHQPFL-UHFFFAOYSA-N

| SMILES = CC(C)N(CCCl)CCCl

}}

| Section2 = {{Chembox Properties

| MeltingPtC = 13.7

| BoilingPtC = 67-68

}}

| Section3 = {{Chembox Hazards

| LD50 = 1.1 mg/kg (subcutaneous, mice)(hydrochloride salt)
1 mg/kg (subcutaneous, rats)(hydrochloride salt)
0.5 mg/kg (intravenous, rat)(hydrochloride salt)
22 mg/kg (oral, mice)(hydrochloride salt)
0.5 mg/kg (subcutaneous, mice)(hydrochloride salt)
2 mg/kg (subcutaneous, rats)(hydrochloride salt)

| LDLo = 25 mg/kg (oral, rats)(hydrochloride salt){{cite book |last1=Witt |first1=James B. De |title=Relationship Between Chemical Structure and Toxic Action on Rats |date=1953 |publisher=Chemical-Biological Coordination Center, National Research Council |url=https://books.google.com/books?id=S3srAAAAYAAJ |language=en}}

}}

}}

TL-301 is a nitrogen mustard vesicant.{{cite web |title=Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. |url=https://ntrl.ntis.gov/NTRL/dashboard/searchResults/titleDetail/PB158508.xhtml |date=1958}}{{cite web |title=Chemical Warfare Agents, and Related Chemical Problems, Parts III-VI-Summary Technical Report. |url=https://ntrl.ntis.gov/NTRL/dashboard/searchResults/titleDetail/PB158507.xhtml}}{{cite journal |last1=Boyland |first1=E |title=The toxicity of alkyl-bis(beta-chloroethyl)amines and of the products of their reaction with water. |journal=British Journal of Pharmacology and Chemotherapy |date=December 1946 |volume=1 |issue=4 |pages=247–54 |doi=10.1111/j.1476-5381.1946.tb00044.x |pmid=19108094|pmc=1509752 }}

See also

References

{{reflist}}

{{Chemical agents}}

{{Nitrogen mustards}}

Category:Nitrogen mustard vesicants

Category:Chloroethyl compounds

Category:Isopropylamino compounds

{{Amine-stub}}