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TLX2

{{Short description|Human protein-coding gene}}

{{Infobox_gene}}

T-cell leukemia homeobox protein 2 is a protein that in humans is encoded by the TLX2 gene.{{cite journal | vauthors = Puliti A, Cinti R, Betsos N, Romeo G, Ceccherini I | title = HOX11L1, a gene involved in peripheral nervous system development, maps to human chromosome 2p13.1→p12 and mouse chromosome 6C3-D1 | journal = Cytogenetics and Cell Genetics | volume = 84 | issue = 1–2 | pages = 115–7 | date = Jun 1999 | pmid = 10343123 | doi = 10.1159/000015234 | s2cid = 21498122 }}{{cite web | title = Entrez Gene: TLX2 T-cell leukemia homeobox 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3196}}

Interactions

TLX2 has been shown to interact with YWHAH.{{cite journal | vauthors = Tang SJ, Suen TC, McInnes RR, Buchwald M | title = Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins | journal = The Journal of Biological Chemistry | volume = 273 | issue = 39 | pages = 25356–63 | date = September 1998 | pmid = 9738002 | doi = 10.1074/jbc.273.39.25356 | doi-access = free }}

References

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Further reading

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  • {{cite journal | vauthors = Kaifi JT, Wagner M, Schurr PG, Wachowiak R, Reichelt U, Yekebas EF, Mann O, Vashist Y, Kleinhans H, Link BC, Strate T, Kalinin V, Izbicki JR | title = Allelic loss of Hox11L1 gene locus predicts outcome of gastrointestinal stromal tumors | journal = Oncology Reports | volume = 16 | issue = 4 | pages = 915–9 | date = October 2006 | pmid = 16969514 | doi = 10.3892/or.16.4.915 | doi-access = free }}
  • {{cite journal | vauthors = Borghini S, Bachetti T, Fava M, Di Duca M, Cargnin F, Fornasari D, Ravazzolo R, Ceccherini I | title = The TLX2 homeobox gene is a transcriptional target of PHOX2B in neural-crest-derived cells | journal = The Biochemical Journal | volume = 395 | issue = 2 | pages = 355–61 | date = April 2006 | pmid = 16402914 | pmc = 1422762 | doi = 10.1042/BJ20051386 }}
  • {{cite journal | vauthors = Parisi MA, Lipman NS, Clarke CM, Taylor B, Kapur RP | title = Evaluation of Hox11L1 in the fmc/fmc rat model of chronic intestinal pseudo-obstruction | journal = Journal of Pediatric Surgery | volume = 40 | issue = 11 | pages = 1760–5 | date = November 2005 | pmid = 16291166 | doi = 10.1016/j.jpedsurg.2005.07.010 }}
  • {{cite journal | vauthors = Iitsuka Y, Shimizu H, Kang MM, Sasagawa K, Sekiya S, Tokuhisa T, Hatano M | title = An enhancer element for expression of the Ncx (Enx, Hox11L1) gene in neural crest-derived cells | journal = The Journal of Biological Chemistry | volume = 274 | issue = 34 | pages = 24401–7 | date = August 1999 | pmid = 10446220 | doi = 10.1074/jbc.274.34.24401 | doi-access = free }}
  • {{cite journal | vauthors = Tang SJ, Suen TC, McInnes RR, Buchwald M | title = Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins | journal = The Journal of Biological Chemistry | volume = 273 | issue = 39 | pages = 25356–63 | date = September 1998 | pmid = 9738002 | doi = 10.1074/jbc.273.39.25356 | doi-access = free }}

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{{Transcription factors and intracellular receptors|g3}}

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