TMEM219

{{Short description|Protein-coding gene in the species Homo sapiens}}

Transmembrane protein 219 also known as insulin-like growth factor-binding protein 3 receptor or IGFBP-3R is a protein that in humans is encoded by the TMEM219 gene.{{cite web | title = Entrez Gene: Transmembrane protein 219 | url = https://www.ncbi.nlm.nih.gov/gene/124446 }} IGFBP-3R acts as a cell death receptor for IGFBP3.{{cite journal |vauthors=Ingermann AR, Yang YF, Han J, Mikami A, Garza AE, Mohanraj L, Fan L, Idowu M, Ware JL, Kim HS, Lee DY, Oh Y | title = Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer | journal = J. Biol. Chem. | volume = 285 | issue = 39 | pages = 30233–46 |date=September 2010 | pmid = 20353938 | pmc = 2943278 | doi = 10.1074/jbc.M110.122226 | doi-access = free }}

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