TMPRSS4

{{Short description|Protein-coding gene in the species Homo sapiens}}

Transmembrane protease, serine 4 is a protein in humans that is encoded by the TMPRSS4 gene.

{{cite web

| title = Entrez Gene: Transmembrane protease, serine 4

| url = https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=56649

| accessdate = 2012-10-30

}}

This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.