TPD52L2

TPD52L2 has been shown to interact with TPD52L1 and TPD52.

TPD52L2 has a role in membrane traffic.{{cite journal | vauthors = Larocque G, La-Borde PJ, Clarke NI, Carter NJ, Royle SJ | title = Tumor protein D54 defines a new class of intracellular transport vesicle | journal = J Cell Biol | volume = 219| year = 2019 | issue = 1 | pmid = 31672706 | doi = 10.1083/jcb.201812044 | pmc = 7039206 | doi-access = free }} TPD52L2 is found on small transport vesicles, termed intracellular nanovesicles, that transfer proteins between different cellular compartments. When TPD52L2 is depleted from HeLa cells, the following trafficking pathways are impaired: anterograde traffic, recycling of cargo and Golgi integrity. Proteomic analysis indicates that TPD52L2 is one of the most abundant proteins expressed in HeLa cells.{{cite journal | vauthors = Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M | title = A human interactome in three quantitative dimensions organized by stoichiometries and abundances | journal = Cell | volume = 163 | issue = 3 | pages = 712–23 | year = 2017 | pmid = 26496610 | doi = 10.1016/j.cell.2015.09.053 | doi-access = free }}

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• {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
• {{cite journal | vauthors = Byrne JA, Mattei MG, Basset P | title = Definition of the tumor protein D52 (TPD52) gene family through cloning of D52 homologues in human (hD53) and mouse (mD52) | journal = Genomics | volume = 35 | issue = 3 | pages = 523–32 | year = 1996 | pmid = 8812487 | doi = 10.1006/geno.1996.0393 }}
• {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
• {{cite journal | vauthors = Nourse CR, Mattei MG, Gunning P, Byrne JA | title = Cloning of a third member of the D52 gene family indicates alternative coding sequence usage in D52-like transcripts | journal = Biochim. Biophys. Acta | volume = 1443 | issue = 1–2 | pages = 155–68 | year = 1998 | pmid = 9838088 | doi = 10.1016/S0167-4781(98)00211-5 }}
• {{cite journal | vauthors = Wilson SH, Bailey AM, Nourse CR, Mattei MG, Byrne JA | title = Identification of MAL2, a novel member of the mal proteolipid family, though interactions with TPD52-like proteins in the yeast two-hybrid system | journal = Genomics | volume = 76 | issue = 1–3 | pages = 81–8 | year = 2001 | pmid = 11549320 | doi = 10.1006/geno.2001.6610 }}
• {{cite journal | vauthors = Boutros R, Byrne JA | title = D53 (TPD52L1) is a cell cycle-regulated protein maximally expressed at the G2-M transition in breast cancer cells | journal = Exp. Cell Res. | volume = 310 | issue = 1 | pages = 152–65 | year = 2005 | pmid = 16112108 | doi = 10.1016/j.yexcr.2005.07.009 }}
• {{cite journal | vauthors = Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S | title = Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes | journal = Genome Res. | volume = 16 | issue = 1 | pages = 55–65 | year = 2006 | pmid = 16344560 | pmc = 1356129 | doi = 10.1101/gr.4039406 }}
• {{cite journal | vauthors = Barbaric D, Byth K, Dalla-Pozza L, Byrne JA | title = Expression of tumor protein D52-like genes in childhood leukemia at diagnosis: clinical and sample considerations | journal = Leuk. Res. | volume = 30 | issue = 11 | pages = 1355–63 | year = 2006 | pmid = 16620967 | doi = 10.1016/j.leukres.2006.03.009 }}
• {{cite journal | vauthors = Cao Q, Chen J, Zhu L, Liu Y, Zhou Z, Sha J, Wang S, Li J | title = A testis-specific and testis developmentally regulated tumor protein D52 (TPD52)-like protein TPD52L3/hD55 interacts with TPD52 family proteins | journal = Biochem. Biophys. Res. Commun. | volume = 344 | issue = 3 | pages = 798–806 | year = 2006 | pmid = 16631610 | doi = 10.1016/j.bbrc.2006.03.208 }}
• {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 | s2cid = 7827573 | doi-access = free }}

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Category:Genes mutated in mice

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