TRAPPC9

This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.

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• {{cite journal |vauthors=Hu WH, Pendergast JS, Mo XM, Brambilla R, Bracchi-Ricard V, Li F, Walters WM, Blits B, He L, Schaal SM, Bethea JR |title=NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation |journal=J. Biol. Chem. |volume=280 |issue=32 |pages=29233–41 |year=2005 |pmid=15951441 |pmc=3707486 |doi=10.1074/jbc.M501670200 |doi-access=free }}
• {{cite journal |vauthors=Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y |title=Association of gene polymorphisms with chronic kidney disease in Japanese individuals |journal=Int. J. Mol. Med. |volume=24 |issue=4 |pages=539–47 |year=2009 |pmid=19724895 |doi= 10.3892/ijmm_00000263|doi-access=free }}
• {{cite journal |vauthors=Oguri M, Kato K, Yokoi K, Yoshida T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y |title=Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals |journal=Am. J. Hypertens. |volume=23 |issue=1 |pages=70–7 |year=2010 |pmid=19851296 |doi=10.1038/ajh.2009.190 |doi-access=free }}
• {{cite journal |vauthors=Mochida GH, Mahajnah M, Hill AD, Basel-Vanagaite L, Gleason D, Hill RS, Bodell A, Crosier M, Straussberg R, Walsh CA |title=A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly |journal=Am. J. Hum. Genet. |volume=85 |issue=6 |pages=897–902 |year=2009 |pmid=20004763 |pmc=2790576 |doi=10.1016/j.ajhg.2009.10.027 }}
• {{cite journal |vauthors=Mir A, Kaufman L, Noor A, Motazacker MM, Jamil T, Azam M, Kahrizi K, Rafiq MA, Weksberg R, Nasr T, Naeem F, Tzschach A, Kuss AW, Ishak GE, Doherty D, Ropers HH, Barkovich AJ, Najmabadi H, Ayub M, Vincent JB |title=Identification of mutations in TRAPPC9, which encodes the NIK- and IKK-beta-binding protein, in nonsyndromic autosomal-recessive mental retardation |journal=Am. J. Hum. Genet. |volume=85 |issue=6 |pages=909–15 |year=2009 |pmid=20004765 |pmc=2790571 |doi=10.1016/j.ajhg.2009.11.009 }}
• {{cite journal |vauthors=Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y |title=Association of genetic variants with hemorrhagic stroke in Japanese individuals |journal=Int. J. Mol. Med. |volume=25 |issue=4 |pages=649–56 |year=2010 |pmid=20198315 |doi= 10.3892/ijmm_00000388|doi-access=free }}
• {{cite journal |vauthors=Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR |title=Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score |journal=Mol. Med. |volume=16 |issue=7–8 |pages=247–53 |year=2010 |pmid=20379614 |pmc=2896464 |doi=10.2119/molmed.2009.00159 }}
• {{cite journal |vauthors=Barrowman J, Bhandari D, Reinisch K, Ferro-Novick S |title=TRAPP complexes in membrane traffic: convergence through a common Rab |journal=Nat. Rev. Mol. Cell Biol. |volume=11 |issue=11 |pages=759–63 |year=2010 |pmid=20966969 |doi=10.1038/nrm2999 |s2cid=20099084 }}
• {{cite journal |vauthors=Zong M, Wu XG, Chan CW, Choi MY, Chan HC, Tanner JA, Yu S |title=The adaptor function of TRAPPC2 in mammalian TRAPPs explains TRAPPC2-associated SEDT and TRAPPC9-associated congenital intellectual disability |journal=PLOS ONE |volume=6 |issue=8 |pages=e23350 |year=2011 |pmid=21858081 |pmc=3156116 |doi=10.1371/journal.pone.0023350 |bibcode=2011PLoSO...623350Z |doi-access=free }}

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