TSPAN6

Tetraspanin-6 is a protein that in humans is encoded by the TSPAN6 gene.{{cite journal | vauthors = Maeda K, Matsuhashi S, Hori K, Xin Z, Mukai T, Tabuchi K, Egashira M, Niikawa N | title = Cloning and characterization of a novel human gene, TM4SF6, encoding a protein belonging to the transmembrane 4 superfamily, and mapped to Xq22 | journal = Genomics | volume = 52 | issue = 2 | pages = 240–2 |date=Dec 1998 | pmid = 9782095 | doi = 10.1006/geno.1998.5415 }}{{cite web | title = Entrez Gene: TSPAN6 tetraspanin 6| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7105}}

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene.

References

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TSPAN6

References

Further reading