TUBE1
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Tubulin, epsilon 1 is a protein in humans that is encoded by the TUBE1 gene.{{cite web | title = Entrez Gene: Tubulin, epsilon 1 | url = https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=51175}}
This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication
References
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Further reading
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- {{cite journal | vauthors = Chang P, Giddings TH, Winey M, Stearns T | title = Epsilon-tubulin is required for centriole duplication and microtubule organization | journal = Nature Cell Biology | volume = 5 | issue = 1 | pages = 71–6 | date = January 2003 | pmid = 12510196 | doi = 10.1038/ncb900 | s2cid = 1318660 }}
- {{cite journal | vauthors = Zanic M, Stear JH, Hyman AA, Howard J | title = EB1 recognizes the nucleotide state of tubulin in the microtubule lattice | journal = PLOS ONE | volume = 4 | issue = 10 | pages = e7585 | date = October 2009 | pmid = 19851462 | pmc = 2761489 | doi = 10.1371/journal.pone.0007585 | bibcode = 2009PLoSO...4.7585Z | editor1-last = May | editor1-first = Robin Charles | doi-access = free }}
- {{cite journal | vauthors = Chang P, Stearns T | title = Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function | journal = Nature Cell Biology | volume = 2 | issue = 1 | pages = 30–5 | date = January 2000 | pmid = 10620804 | doi = 10.1038/71350 | s2cid = 23500269 }}
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