TUBGCP6
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Gamma-tubulin complex component 6 is a protein that in humans is encoded by the TUBGCP6 gene.{{cite journal | vauthors = Murphy SM, Preble AM, Patel UK, O'Connell KL, Dias DP, Moritz M, Agard D, Stults JT, Stearns T | title = GCP5 and GCP6: two new members of the human gamma-tubulin complex | journal = Mol. Biol. Cell | volume = 12 | issue = 11 | pages = 3340–52 | year = 2001 | pmid = 11694571 | pmc = 60259 | doi = 10.1091/mbc.12.11.3340 }}{{cite journal | vauthors = Hirosawa M, Nagase T, Murahashi Y, Kikuno R, Ohara O | title = Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping | journal = DNA Res. | volume = 8 | issue = 1 | pages = 1–9 | year = 2001 | pmid = 11258795 | doi = 10.1093/dnares/8.1.1 | doi-access = free }}{{cite web | title = Entrez Gene: TUBGCP6 tubulin, gamma complex associated protein 6| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=85378}}
It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.
See also
References
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Further reading
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- {{cite journal | vauthors = Oriolo AS, Wald FA, Canessa G, Salas PJ | title = GCP6 binds to intermediate filaments: a novel function of keratins in the organization of microtubules in epithelial cells | journal = Mol. Biol. Cell | volume = 18 | issue = 3 | pages = 781–94 | year = 2007 | pmid = 17182859 | pmc = 1805110 | doi = 10.1091/mbc.E06-03-0201 }}
- {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 101 | issue = 33 | pages = 12130–5 | year = 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 | bibcode = 2004PNAS..10112130B | doi-access = free }}
- {{cite journal | vauthors = Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW | title = Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation | journal = Nat. Biotechnol. | volume = 22 | issue = 6 | pages = 707–16 | year = 2004 | pmid = 15146197 | doi = 10.1038/nbt971 | s2cid = 27764390 }}
- {{cite journal | vauthors = Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP | title = The DNA sequence of human chromosome 22 | journal = Nature | volume = 402 | issue = 6761 | pages = 489–95 | year = 1999 | pmid = 10591208 | doi = 10.1038/990031 | bibcode = 1999Natur.402..489D | doi-access = free }}
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