Tabersonine 16-O-methyltransferase
{{infobox enzyme
| Name = 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase
| EC_number = 2.1.1.94
| CAS_number = 100984-95-0
| GO_code = 0030766
| image =
| width =
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In enzymology, a tabersonine 16-O-methyltransferase ({{EC number|2.1.1.94}}) is an enzyme that catalyzes the chemical reaction
:S-adenosyl-L-methionine + 16-hydroxytabersonine S-adenosyl-L-homocysteine + 16-methoxytabersonine
Thus, the two substrates of this enzyme are S-adenosyl methionine and 16-hydroxytabersonine, whereas its two products are S-adenosylhomocysteine and 16-methoxytabersonine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase. Other names in common use include 11-demethyl-17-deacetylvindoline 11-methyltransferase, 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase, S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline, and 11-O-methyltransferase. This enzyme participates in terpene indole and ipecac alkaloid biosynthesis.
References
{{reflist|1}}
- {{cite journal | vauthors = Foucher AL, McIntosh A, Douce G, Wastling J, Tait A, Turner CM | date = 2006 | title = A proteomic analysis of arsenical drug resistance in Trypanosoma brucei | journal = Proteomics | volume = 6 | pages = 2726–32 | pmid = 16526094 | doi = 10.1002/pmic.200500419 | issue = 9 }}
- {{cite journal | vauthors = Fahn W, Laussermair E, Deus-Neumann B, Stockigt J | date = 1985 | title = Late enzymes of vindoline biosynthesis S-Adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methylase and unspecific acetylesterase | journal = Plant Cell Rep. | volume = 4 | pages = 337–340 | doi=10.1007/bf00269893}}
{{One carbon transferases}}
{{Enzymes}}
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Category:Enzymes of unknown structure
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